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Pharmacokinetics and Anti-Diabetic Studies of Gliclazide Nanosuspension
Gliclazide (GCZ), an antidiabetic medication, has poor solubility and limited oral bioavailability due to substantial first-pass metabolism. Thus, the purpose of the current study was to optimize and formulate a GCZ nanosuspension (NS) employing the antisolvent precipitation technique. A three-facto...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500859/ https://www.ncbi.nlm.nih.gov/pubmed/36145695 http://dx.doi.org/10.3390/pharmaceutics14091947 |