Cargando…

Pharmacokinetics and Anti-Diabetic Studies of Gliclazide Nanosuspension

Gliclazide (GCZ), an antidiabetic medication, has poor solubility and limited oral bioavailability due to substantial first-pass metabolism. Thus, the purpose of the current study was to optimize and formulate a GCZ nanosuspension (NS) employing the antisolvent precipitation technique. A three-facto...

Descripción completa

Detalles Bibliográficos
Autores principales: Sampathi, Sunitha, Prajapati, Shubham, Junnuthula, Vijayabhaskarreddy, Dyawanapelly, Sathish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500859/
https://www.ncbi.nlm.nih.gov/pubmed/36145695
http://dx.doi.org/10.3390/pharmaceutics14091947