Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice

The loss of functional pancreatic β-cell mass is an important hallmark of both type 1 and type 2 diabetes. The RNA-binding protein NOVA1 is expressed in human and rodent pancreatic β-cells. Previous in vitro studies indicated that NOVA1 is necessary for glucose-stimulated insulin secretion and its d...

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Detalles Bibliográficos
Autores principales: Brahma, Manoja K., Xiao, Peng, Popa, Madalina, Negueruela, Javier, Vandenbempt, Valerie, Demine, Stéphane, Cardozo, Alessandra K., Gurzov, Esteban N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500891/
https://www.ncbi.nlm.nih.gov/pubmed/36145242
http://dx.doi.org/10.3390/nu14183866

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