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Viral Metagenomics Reveals Diverse Viruses in Tissue Samples of Diseased Pigs

The swine industry plays an essential role in agricultural production in China. Diseases, especially viral diseases, affect the development of the pig industry and threaten human health. However, at present, the tissue virome of diseased pigs has rarely been studied. Using the unbiased viral metagen...

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Detalles Bibliográficos
Autores principales: Yang, Shixing, Zhang, Dianqi, Ji, Zexuan, Zhang, Yuyang, Wang, Yan, Chen, Xu, He, Yumin, Lu, Xiang, Li, Rong, Guo, Yufei, Shen, Quan, Ji, Likai, Wang, Xiaochun, Li, Yu, Zhang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500892/
https://www.ncbi.nlm.nih.gov/pubmed/36146854
http://dx.doi.org/10.3390/v14092048
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author Yang, Shixing
Zhang, Dianqi
Ji, Zexuan
Zhang, Yuyang
Wang, Yan
Chen, Xu
He, Yumin
Lu, Xiang
Li, Rong
Guo, Yufei
Shen, Quan
Ji, Likai
Wang, Xiaochun
Li, Yu
Zhang, Wen
author_facet Yang, Shixing
Zhang, Dianqi
Ji, Zexuan
Zhang, Yuyang
Wang, Yan
Chen, Xu
He, Yumin
Lu, Xiang
Li, Rong
Guo, Yufei
Shen, Quan
Ji, Likai
Wang, Xiaochun
Li, Yu
Zhang, Wen
author_sort Yang, Shixing
collection PubMed
description The swine industry plays an essential role in agricultural production in China. Diseases, especially viral diseases, affect the development of the pig industry and threaten human health. However, at present, the tissue virome of diseased pigs has rarely been studied. Using the unbiased viral metagenomic approach, we investigated the tissue virome in sick pigs (respiratory symptoms, reproductive disorders, high fever, diarrhea, weight loss, acute death and neurological symptoms) collected from farms of Anhui, Jiangsu and Sichuan Province, China. The eukaryotic viruses identified belonged to the families Anelloviridae, Arteriviridae, Astroviridae, Flaviviridae, Circoviridae and Parvoviridae; prokaryotic virus families including Siphoviridae, Myoviridae and Podoviridae occupied a large proportion in some samples. This study provides valuable information for understanding the tissue virome in sick pigs and for the monitoring, preventing, and treating of viral diseases in pigs.
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spelling pubmed-95008922022-09-24 Viral Metagenomics Reveals Diverse Viruses in Tissue Samples of Diseased Pigs Yang, Shixing Zhang, Dianqi Ji, Zexuan Zhang, Yuyang Wang, Yan Chen, Xu He, Yumin Lu, Xiang Li, Rong Guo, Yufei Shen, Quan Ji, Likai Wang, Xiaochun Li, Yu Zhang, Wen Viruses Article The swine industry plays an essential role in agricultural production in China. Diseases, especially viral diseases, affect the development of the pig industry and threaten human health. However, at present, the tissue virome of diseased pigs has rarely been studied. Using the unbiased viral metagenomic approach, we investigated the tissue virome in sick pigs (respiratory symptoms, reproductive disorders, high fever, diarrhea, weight loss, acute death and neurological symptoms) collected from farms of Anhui, Jiangsu and Sichuan Province, China. The eukaryotic viruses identified belonged to the families Anelloviridae, Arteriviridae, Astroviridae, Flaviviridae, Circoviridae and Parvoviridae; prokaryotic virus families including Siphoviridae, Myoviridae and Podoviridae occupied a large proportion in some samples. This study provides valuable information for understanding the tissue virome in sick pigs and for the monitoring, preventing, and treating of viral diseases in pigs. MDPI 2022-09-15 /pmc/articles/PMC9500892/ /pubmed/36146854 http://dx.doi.org/10.3390/v14092048 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yang, Shixing
Zhang, Dianqi
Ji, Zexuan
Zhang, Yuyang
Wang, Yan
Chen, Xu
He, Yumin
Lu, Xiang
Li, Rong
Guo, Yufei
Shen, Quan
Ji, Likai
Wang, Xiaochun
Li, Yu
Zhang, Wen
Viral Metagenomics Reveals Diverse Viruses in Tissue Samples of Diseased Pigs
title Viral Metagenomics Reveals Diverse Viruses in Tissue Samples of Diseased Pigs
title_full Viral Metagenomics Reveals Diverse Viruses in Tissue Samples of Diseased Pigs
title_fullStr Viral Metagenomics Reveals Diverse Viruses in Tissue Samples of Diseased Pigs
title_full_unstemmed Viral Metagenomics Reveals Diverse Viruses in Tissue Samples of Diseased Pigs
title_short Viral Metagenomics Reveals Diverse Viruses in Tissue Samples of Diseased Pigs
title_sort viral metagenomics reveals diverse viruses in tissue samples of diseased pigs
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500892/
https://www.ncbi.nlm.nih.gov/pubmed/36146854
http://dx.doi.org/10.3390/v14092048
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