Cargando…

Polygonatum sibiricum Polysaccharides Attenuate Lipopoly-Saccharide-Induced Septic Liver Injury by Suppression of Pyroptosis via NLRP3/GSDMD Signals

Sepsis is a systemic inflammatory response syndrome with high mortality. Acute liver injury is an independent predictor for poor prognosis in septic patients. Polygonatum sibiricum polysaccharides (PSP) have been reported to possess anti-inflammatory and hepatoprotective activities. To evaluate the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Linxia, Qi, Liang, Zhang, Guozhe, Liu, Hongxia, Gu, Yaqin, Zhang, Lihu, Zhang, Mingguang, Wu, Hongyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500967/ https://www.ncbi.nlm.nih.gov/pubmed/36144734 http://dx.doi.org/10.3390/molecules27185999

Ejemplares similares

A Review: The Bioactivities and Pharmacological Applications of Polygonatum sibiricum polysaccharides
por: Cui, Xiaowei, et al.
Publicado: (2018)

Determination of polysaccharides composition in Polygonatum sibiricum and Polygonatum odoratum by HPLC-FLD with pre-column derivatization
por: Xu, Sheng, et al.
Publicado: (2022)

Advances in Polygonatum sibiricum polysaccharides: Extraction, purification, structure, biosynthesis, and bioactivity
por: Liu, Dan, et al.
Publicado: (2022)

Effects of Extraction Methods on the Physicochemical Properties and Biological Activities of Polysaccharides from Polygonatum sibiricum
por: Jing, Yongshuai, et al.
Publicado: (2023)

Antioxidant Effect of Polygonatum sibiricum Polysaccharides in D-Galactose-Induced Heart Aging Mice
por: Ma, Wanjun, et al.
Publicado: (2021)

Polygonatum sibiricum polysaccharide potentially attenuates diabetic retinal injury in a diabetic rat model
por: Wang, Yi, et al.
Publicado: (2018)

Hypolipidemic Activity and Antiatherosclerotic Effect of Polysaccharide of Polygonatum sibiricum in Rabbit Model and Related Cellular Mechanisms
por: Yang, Jun-xuan, et al.
Publicado: (2015)

Corrigendum to “Antioxidant Effect of Polygonatum sibiricum Polysaccharides in D-Galactose-Induced Heart Aging Mice”
por: Ma, Wanjun, et al.
Publicado: (2021)

Protective effect of Polygonatum sibiricum Polysaccharide on D-galactose-induced aging rats model
por: Zheng, Shaoyan
Publicado: (2020)

Construction of Polygonatum sibiricum Polysaccharide Functionalized Selenium Nanoparticles for the Enhancement of Stability and Antioxidant Activity
por: Chen, Wanwen, et al.
Publicado: (2022)

Benefits of neutral polysaccharide from rhizomes of Polygonatum sibiricum to intestinal function of aged mice
por: Li, Li-Xia, et al.
Publicado: (2022)

Research on the Impact of Deep Eutectic Solvent and Hot-Water Extraction Methods on the Structure of Polygonatum sibiricum Polysaccharides
por: Zhang, Chunyan, et al.
Publicado: (2023)

De Novo Assembly and Analysis of Polygonatum sibiricum Transcriptome and Identification of Genes Involved in Polysaccharide Biosynthesis
por: Wang, Shiqiang, et al.
Publicado: (2017)

Cloning and Characterization of the Gene Encoding HMGS Synthase in Polygonatum sibiricum
por: Jiang, Yujie, et al.
Publicado: (2022)

Polygonatum sibiricum Polysaccharides Protect against MPP-Induced Neurotoxicity via the Akt/mTOR and Nrf2 Pathways
por: Huang, Si, et al.
Publicado: (2021)

Metabolome and transcriptome signatures shed light on the anti-obesity effect of Polygonatum sibiricum
por: Ou, Xiaobin, et al.
Publicado: (2023)

Polysaccharides from the leaves of Polygonatum sibiricum Red. regulate the gut microbiota and affect the production of short-chain fatty acids in mice
por: Luo, Yu, et al.
Publicado: (2022)

SSR Loci Analysis in Transcriptome and Molecular Marker Development in Polygonatum sibiricum
por: Yang, Qingwen, et al.
Publicado: (2022)

Ceramide induces pyroptosis through TXNIP/NLRP3/GSDMD pathway in HUVECs
por: Liu, Fangfang, et al.
Publicado: (2022)

Effects of steam on polysaccharides from Polygonatum cyrtonema based on saccharide mapping analysis and pharmacological activity assays
por: Chen, Zherui, et al.
Publicado: (2022)

Blood-Enriching Effects and Immune-Regulation Mechanism of Steam-Processed Polygonatum Sibiricum Polysaccharide in Blood Deficiency Syndrome Mice
por: Wang, Juan, et al.
Publicado: (2022)

Insights into the mechanisms of microbiome and metabolome changes mediated by understory interplanting mode in Polygonatum sibiricum
por: Wang, Yue, et al.
Publicado: (2023)

Anti-cancer Potential of Polysaccharide Extracted From Polygonatum sibiricum on HepG2 Cells via Cell Cycle Arrest and Apoptosis
por: Li, Mo, et al.
Publicado: (2022)

Efficacy of Polygonatum sibiricum on Mild Insomnia: A Randomized Placebo-Controlled Trial
por: Ha, Eunji, et al.
Publicado: (2019)

Characterization, Classification, and Authentication of Polygonatum sibiricum Samples by Volatile Profiles and Flavor Properties
por: Cheng, Xile, et al.
Publicado: (2021)

Effects of Polygonatum sibiricum on Physicochemical Properties, Biological Compounds, and Functionality of Fermented Soymilk
por: Wan, Peng, et al.
Publicado: (2023)

Polygonatum sibiricum polysaccharide inhibits osteoporosis by promoting osteoblast formation and blocking osteoclastogenesis through Wnt/β-catenin signalling pathway
por: Du, Li, et al.
Publicado: (2016)

Mechanochemical prepared ibuprofen-Polygonatum sibiricum polysaccharide drug delivery system for enhanced bioactivity with reduced renal injury induced by NSAIDs
por: Xu, Wenhao, et al.
Publicado: (2022)

Polygonatum sibiricum F. Delaroche polysaccharide ameliorates HFD-induced mouse obesity via regulation of lipid metabolism and inflammatory response
por: Liu, Bo, et al.
Publicado: (2021)

Use of Steaming Process to Improve Biochemical Activity of Polygonatum sibiricum Polysaccharides against D-Galactose-Induced Memory Impairment in Mice
por: Bian, Zhijuan, et al.
Publicado: (2022)

Hypoglycemic mechanisms of Polygonatum sibiricum polysaccharide in db/db mice via regulation of glycolysis/gluconeogenesis pathway and alteration of gut microbiota
por: Chen, Xuan, et al.
Publicado: (2023)

A New Method of Extracting Polygonatum sibiricum Polysaccharide with Antioxidant Function: Ultrasound-Assisted Extraction-Deep Eutectic Solvents Method
por: Sun, Chaoqun, et al.
Publicado: (2023)

Corrigendum: Anti-cancer potential of polysaccharide extracted from Polygonatum sibiricum on HepG2 cells via cell cycle arrest and apoptosis
por: Li, Mo, et al.
Publicado: (2022)

An Evaluation of Traits, Nutritional, and Medicinal Component Quality of Polygonatum cyrtonema Hua and P. sibiricum Red.
por: Hu, Yan, et al.
Publicado: (2022)

RAW264.7 Cell Activating Glucomannans Extracted from Rhizome of Polygonatum sibiricum
por: Yelithao, Khamphone, et al.
Publicado: (2016)

Synthesis of naphthalimide-type chemsensor and its application in quality evaluation for polygonatum sibiricum Red
por: Wang, Zhen, et al.
Publicado: (2022)

Polygonatum sibiricum polysaccharides (PSP) improve the palmitic acid (PA)-induced inhibition of survival, inflammation, and glucose uptake in skeletal muscle cells
por: Cai, Jia-Luo, et al.
Publicado: (2021)

Characterization of the complete chloroplast genome of Polygonatum sibiricum (Liliaceae), a well-known herb to China
por: Pan, Jiaoyi, et al.
Publicado: (2020)

Emodin Alleviates High-Glucose-Induced Pancreatic β-Cell Pyroptosis by Inhibiting NLRP3/GSDMD Signaling
por: Xing, Yiqian, et al.
Publicado: (2022)

Identification of Antitumor Active Constituents in Polygonatum sibiricum Flower by UPLC-Q-TOF-MS(E) and Network Pharmacology
por: Huang, Zhuang-zhuang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_abjfs4vskfpge2ak13ij98tb5k