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Investigation of Alogliptin-Loaded In Situ Gel Implants by 2(3) Factorial Design with Glycemic Assessment in Rats
The aim of the study was to design injectable long-acting poly (lactide-co-glycolide) (PLGA)-based in situ gel implants (ISGI) loaded with the anti-diabetic alogliptin. Providing sustained therapeutic exposures and improving the pharmacological responses of alogliptin were targeted for achieving red...
Autores principales: | Ibrahim, Tarek M., Ayoub, Margrit M., El-Bassossy, Hany M., El-Nahas, Hanan M., Gomaa, Eman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501034/ https://www.ncbi.nlm.nih.gov/pubmed/36145615 http://dx.doi.org/10.3390/pharmaceutics14091867 |
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