Gallic Acid Alkyl Esters: Trypanocidal and Leishmanicidal Activity, and Target Identification via Modeling Studies

Eight gallic acid alkyl esters (1–8) were synthesized via Fischer esterification and evaluated for their trypanocidal and leishmanicidal activity using bloodstream forms of Trypanosoma brucei and promastigotes of Leishmania major. The general cytotoxicity of the esters was evaluated with human HL-60...

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Detalles Bibliográficos
Autores principales: Steverding, Dietmar, do Nascimento, Lázaro Gomes, Perez-Castillo, Yunierkis, de Sousa, Damião Pergentino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501172/
https://www.ncbi.nlm.nih.gov/pubmed/36144611
http://dx.doi.org/10.3390/molecules27185876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501172/
https://www.ncbi.nlm.nih.gov/pubmed/36144611
http://dx.doi.org/10.3390/molecules27185876

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