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Gallic Acid Alkyl Esters: Trypanocidal and Leishmanicidal Activity, and Target Identification via Modeling Studies
Eight gallic acid alkyl esters (1–8) were synthesized via Fischer esterification and evaluated for their trypanocidal and leishmanicidal activity using bloodstream forms of Trypanosoma brucei and promastigotes of Leishmania major. The general cytotoxicity of the esters was evaluated with human HL-60...
Autores principales: | Steverding, Dietmar, do Nascimento, Lázaro Gomes, Perez-Castillo, Yunierkis, de Sousa, Damião Pergentino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501172/ https://www.ncbi.nlm.nih.gov/pubmed/36144611 http://dx.doi.org/10.3390/molecules27185876 |
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