Cargando…

Farnesiferol C Exerts Antiproliferative Effects on Hepatocellular Carcinoma HepG2 Cells by Instigating ROS-Dependent Apoptotic Pathway

Farnesiferol C (Far-C) is a coumarin commonly extracted from Ferula asafetida and is popularly used as a traditional source of natural remedy. Liver cancer or hepatocellular carcinoma (HCC) has emerged as a major cause behind cancer burden, and limited therapeutic interventions have further aggravat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alafnan, Ahmed, Alamri, Abdulwahab, Alanazi, Jowaher, Hussain, Talib
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501262/ https://www.ncbi.nlm.nih.gov/pubmed/36145291 http://dx.doi.org/10.3390/ph15091070

Ejemplares similares

Cucurbitacin-B Exerts Anticancer Effects through Instigation of Apoptosis and Cell Cycle Arrest within Human Prostate Cancer PC3 Cells via Downregulating JAK/STAT Signaling Cascade
por: Alafnan, Ahmed, et al.
Publicado: (2022)

Antiproliferative and Apoptotic Effects of Cardamonin against Hepatocellular Carcinoma HepG2 Cells
por: Badroon, Nassrin A., et al.
Publicado: (2020)

Prostate Apoptotic Induction and NFκB Suppression by Dammarolic Acid: Mechanistic Insight into Onco-Therapeutic Action of an Aglycone Asiaticoside
por: Alafnan, Ahmed, et al.
Publicado: (2021)

Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells
por: Dai, Zhi-Jun, et al.
Publicado: (2013)

Cucurbitacin-B instigates intrinsic apoptosis and modulates Notch signaling in androgen-dependent prostate cancer LNCaP cells
por: Alafnan, Ahmed, et al.
Publicado: (2023)

Corrigendum: Cucurbitacin-B instigates intrinsic apoptosis and modulates Notch signaling in androgen-dependent prostate cancer LNCaP cells
por: Alafnan, Ahmed, et al.
Publicado: (2023)

Sida rhombifolia Exerts Anti-Proliferative and Pro-Apoptotic Effects in Human Liver Cancer HepG2 Cells in Vitro
por: Ahmadi, Mohadeseh, et al.
Publicado: (2022)

Antiproliferative and Pro-Apoptotic Effect of Uvaol in Human Hepatocarcinoma HepG2 Cells by Affecting G(0)/G(1) Cell Cycle Arrest, ROS Production and AKT/PI3K Signaling Pathway
por: Bonel-Pérez, Gloria C., et al.
Publicado: (2020)

Infliximab Exerts No Direct Hepatotoxic Effect on HepG2 Cells In Vitro
por: de Vries, Hilbert S., et al.
Publicado: (2012)

Effects of cordycepin on HepG2 and EA.hy926 cells: Potential antiproliferative, antimetastatic and anti-angiogenic effects on hepatocellular carcinoma
por: LU, HAISHENG, et al.
Publicado: (2014)

Effect of yellowing time on bioactive compounds in yellow tea and their antiproliferative capacity in HepG2 cells
por: An, Ran, et al.
Publicado: (2019)

Antiproliferative Effects of Ferulic, Coumaric, and Caffeic Acids in HepG2 Cells by hTERT Downregulation
por: Afshari, Afsoon, et al.
Publicado: (2022)

Preparation and Characterization of an Oyster Peptide–Zinc Complex and Its Antiproliferative Activity on HepG(2) Cells
por: Peng, Bo, et al.
Publicado: (2023)

Delisheng, a Chinese medicinal compound, exerts anti-proliferative and pro-apoptotic effects on HepG2 cells through extrinsic and intrinsic pathways
por: Lu, Chuang-xin, et al.
Publicado: (2009)

Apoptotic and Inhibitory Effects on Cell Proliferation of Hepatocellular Carcinoma HepG2 Cells by Methanol Leaf Extract of Costus speciosus
por: Nair, Sandhya V. G., et al.
Publicado: (2014)

Pro-apoptotic and cytotoxic effects of enriched fraction of Elytranthe parasitica (L.) Danser against HepG2 Hepatocellular carcinoma
por: Kumar, Nimmy, et al.
Publicado: (2016)

A Novel Anti-Hepatitis C Virus and Antiproliferative Agent Alters Metabolic Networks in HepG2 and Hep3B Cells
por: Keogh, Adrian, et al.
Publicado: (2017)

Antiproliferative Activity of the Chinese Medicinal Compound, Delisheng, Compared With Rg3 and Gemcitabine in HepG2 Cells
por: Wang, S. H., et al.
Publicado: (2013)

Antiproliferative Effect of the Isoquinoline Alkaloid Papaverine in Hepatocarcinoma HepG-2 Cells — Inhibition of Telomerase and Induction of Senescence
por: Noureini, Sakineh Kazemi, et al.
Publicado: (2014)

Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation
por: Yu, Rong, et al.
Publicado: (2014)

Encapsulation of Lovastatin in Zein Nanoparticles Exhibits Enhanced Apoptotic Activity in HepG2 Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2019)

Overexpression of activating transcription factor 3 exerts suppressive effects in HepG2 cells
por: Li, Xiaoyan, et al.
Publicado: (2019)

Mitochondrial ROS contribute to oridonin-induced HepG2 apoptosis through PARP activation
por: Liu, Xiaoning, et al.
Publicado: (2018)

Can Natural Products Targeting EMT Serve as the Future Anticancer Therapeutics?
por: Anwar, Sirajudheen, et al.
Publicado: (2022)

Identification of Target Genes Involved in the Antiproliferative Effect of Enzyme-Modified Ginseng Extract in HepG2 Hepatocarcinoma Cell
por: Jang, Sung-Il, et al.
Publicado: (2013)

Potentiation of LPS-Induced Apoptotic Cell Death in Human Hepatoma HepG2 Cells by Aspirin via ROS and Mitochondrial Dysfunction: Protection by N-Acetyl Cysteine
por: Raza, Haider, et al.
Publicado: (2016)

Evaluation of Apoptotic Gene Expression in Hepatoma Cell Line (HepG2) Following Nisin Treatment
por: Zainodini, Nahid, et al.
Publicado: (2021)

Multiplexed Fluorescence Plate Reader In Situ Protein Expression Assay in Apoptotic HepG2 Cells
por: Jakabfi-Csepregi, Rita, et al.
Publicado: (2023)

Effects of Farnesiferol B on Ischemia-Reperfusion-Induced Renal Damage, Inflammation, and NF-κB Signaling
por: Zhang, Lu, et al.
Publicado: (2019)

Antiproliferative Effect and Mediation of Apoptosis in Human Hepatoma HepG2 Cells Induced by Djulis Husk and Its Bioactive Compounds
por: Tu, Dom-Gene, et al.
Publicado: (2020)

Hydroxyethyl Starch Curcumin Enhances Antiproliferative Effect of Curcumin Against HepG2 Cells via Apoptosis and Autophagy Induction
por: Jiang, Linhai, et al.
Publicado: (2021)

Nomad Jellyfish Rhopilema nomadica Venom Induces Apoptotic Cell Death and Cell Cycle Arrest in Human Hepatocellular Carcinoma HepG2 Cells
por: Tawfik, Mohamed M., et al.
Publicado: (2021)

Synergistic Pro-Apoptotic Effect of a Cyclic RGD Peptide-Conjugated Magnetic Mesoporous Therapeutic Nanosystem on Hepatocellular Carcinoma HepG2 Cells
por: Zhao, Xuanping, et al.
Publicado: (2023)

Cytotoxic and apoptotic effects of six herbal plants against the human hepatocarcinoma (HepG2) cell line
por: Machana, Sasipawan, et al.
Publicado: (2011)

Crambescin C1 Exerts a Cytoprotective Effect on HepG2 Cells through Metallothionein Induction
por: Roel, María, et al.
Publicado: (2015)

Naringenin and Quercetin Exert Contradictory Cytoprotective and Cytotoxic Effects on Tamoxifen-Induced Apoptosis in HepG2 Cells
por: Xu, Zhixiang, et al.
Publicado: (2022)

Surfactin-Induced Apoptosis Through ROS–ERS–Ca(2+)-ERK Pathways in HepG2 Cells
por: Wang, Chun-ling, et al.
Publicado: (2013)

Germacrone induces caspase-3/GSDME activation and enhances ROS production, causing HepG2 pyroptosis
por: Sun, Xinfeng, et al.
Publicado: (2022)

Farnesiferol C induces cell cycle arrest and apoptosis mediated by oxidative stress in MCF-7 cell line
por: Hasanzadeh, Davoud, et al.
Publicado: (2017)

Embelin-induced apoptosis of HepG2 human hepatocellular carcinoma cells and blockade of HepG2 cells in the G2/M phase via the mitochondrial pathway
por: TAGHIYEV, ASAF, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_gig6bndue9j39vc26kcgj9s8pe