Synthesis of C(7)/C(8)-cyclitols and C(7)N-aminocyclitols from maltose and X-ray crystal structure of Streptomyces coelicolor GlgEI V279S in a complex with an amylostatin GXG–like derivative

C(7)/C(8)-cyclitols and C(7)N-aminocyclitols find applications in the pharmaceutical sector as α-glucosidase inhibitors and in the agricultural sector as fungicides and insecticides. In this study, we identified C(7)/C(8)-cyclitols and C(7)N-aminocyclitols as potential inhibitors of Streptomyces coe...

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Detalles Bibliográficos
Autores principales: Thanvi, Radhika, Jayasinghe, Thilina D., Kapil, Sunayana, Obadawo, Babatunde Samuel, Ronning, Donald R., Sucheck, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501709/
https://www.ncbi.nlm.nih.gov/pubmed/36157042
http://dx.doi.org/10.3389/fchem.2022.950433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501709/
https://www.ncbi.nlm.nih.gov/pubmed/36157042
http://dx.doi.org/10.3389/fchem.2022.950433

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