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Synthesis of C(7)/C(8)-cyclitols and C(7)N-aminocyclitols from maltose and X-ray crystal structure of Streptomyces coelicolor GlgEI V279S in a complex with an amylostatin GXG–like derivative
C(7)/C(8)-cyclitols and C(7)N-aminocyclitols find applications in the pharmaceutical sector as α-glucosidase inhibitors and in the agricultural sector as fungicides and insecticides. In this study, we identified C(7)/C(8)-cyclitols and C(7)N-aminocyclitols as potential inhibitors of Streptomyces coe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501709/ https://www.ncbi.nlm.nih.gov/pubmed/36157042 http://dx.doi.org/10.3389/fchem.2022.950433 |