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Rag2 Deficiency Enhances Susceptibility to Systemic Mouse Adenovirus Type 1 Infection

INTRODUCTION: Recombination-activating gene (Rag) 1 and Rag2, which are essential in V(D)J recombination, play a crucial role in B- and T-cell maturation. METHOD: We investigated the effects of Rag2 deficiency in clustered regularly interspaced short palindromic repeats/Cas9-mediated FVB-Rag2 knocko...

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Detalles Bibliográficos
Autores principales:	Lee, Han-Kyul, Seo, Sun-Min, Kim, Jun-Young, Kim, Han-Woong, Jeong, Eui-Suk, Choi, Yang-Kyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501770/ https://www.ncbi.nlm.nih.gov/pubmed/34736262 http://dx.doi.org/10.1159/000520463

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