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Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become a major public health worldwide. Hepatic dysfunction has been seen in patients with COVID-19 and could be related to a viral cytopathic effect, an exacerbated immune r...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501835/ https://www.ncbi.nlm.nih.gov/pubmed/36145486 http://dx.doi.org/10.3390/pathogens11091054 |
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author | da Costa, Vanessa Duarte Wiggers, Wilian Jean Ivantes, Claudia Alexandra Pontes da Fonseca, Rodrigo Jardim Monteiro Dávila, Alberto Martín Rivera Moreira, Otacilio C. Ferreira, Beatriz Iandra da Silva de Paula, Vanessa Salete da Silva, Lucas Lima Santos, Alanna Calheiros Villar, Livia Melo |
author_facet | da Costa, Vanessa Duarte Wiggers, Wilian Jean Ivantes, Claudia Alexandra Pontes da Fonseca, Rodrigo Jardim Monteiro Dávila, Alberto Martín Rivera Moreira, Otacilio C. Ferreira, Beatriz Iandra da Silva de Paula, Vanessa Salete da Silva, Lucas Lima Santos, Alanna Calheiros Villar, Livia Melo |
author_sort | da Costa, Vanessa Duarte |
collection | PubMed |
description | The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become a major public health worldwide. Hepatic dysfunction has been seen in patients with COVID-19 and could be related to a viral cytopathic effect, an exacerbated immune reaction, or drug-induced liver damage. Currently, routine modification of immunosuppressive therapy in patients with autoimmune hepatitis (AIH) before and after SARS-CoV-2 infection remains an important topic to be discussed. However, there is little evidence about this thematic to support any recommendation. Here, we described a case report in which the use of an immunosuppressive drug by a patient with diagnosed AIH might have influenced the COVID-19 clinical course with altered laboratory hematological and biochemical parameters during infection. |
format | Online Article Text |
id | pubmed-9501835 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95018352022-09-24 Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient da Costa, Vanessa Duarte Wiggers, Wilian Jean Ivantes, Claudia Alexandra Pontes da Fonseca, Rodrigo Jardim Monteiro Dávila, Alberto Martín Rivera Moreira, Otacilio C. Ferreira, Beatriz Iandra da Silva de Paula, Vanessa Salete da Silva, Lucas Lima Santos, Alanna Calheiros Villar, Livia Melo Pathogens Case Report The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become a major public health worldwide. Hepatic dysfunction has been seen in patients with COVID-19 and could be related to a viral cytopathic effect, an exacerbated immune reaction, or drug-induced liver damage. Currently, routine modification of immunosuppressive therapy in patients with autoimmune hepatitis (AIH) before and after SARS-CoV-2 infection remains an important topic to be discussed. However, there is little evidence about this thematic to support any recommendation. Here, we described a case report in which the use of an immunosuppressive drug by a patient with diagnosed AIH might have influenced the COVID-19 clinical course with altered laboratory hematological and biochemical parameters during infection. MDPI 2022-09-16 /pmc/articles/PMC9501835/ /pubmed/36145486 http://dx.doi.org/10.3390/pathogens11091054 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report da Costa, Vanessa Duarte Wiggers, Wilian Jean Ivantes, Claudia Alexandra Pontes da Fonseca, Rodrigo Jardim Monteiro Dávila, Alberto Martín Rivera Moreira, Otacilio C. Ferreira, Beatriz Iandra da Silva de Paula, Vanessa Salete da Silva, Lucas Lima Santos, Alanna Calheiros Villar, Livia Melo Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient |
title | Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient |
title_full | Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient |
title_fullStr | Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient |
title_full_unstemmed | Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient |
title_short | Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient |
title_sort | characteristics of covid-19 infection in a hospitalized autoimmune hepatitis patient |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501835/ https://www.ncbi.nlm.nih.gov/pubmed/36145486 http://dx.doi.org/10.3390/pathogens11091054 |
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