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Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become a major public health worldwide. Hepatic dysfunction has been seen in patients with COVID-19 and could be related to a viral cytopathic effect, an exacerbated immune r...

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Autores principales: da Costa, Vanessa Duarte, Wiggers, Wilian Jean, Ivantes, Claudia Alexandra Pontes, da Fonseca, Rodrigo Jardim Monteiro, Dávila, Alberto Martín Rivera, Moreira, Otacilio C., Ferreira, Beatriz Iandra da Silva, de Paula, Vanessa Salete, da Silva, Lucas Lima, Santos, Alanna Calheiros, Villar, Livia Melo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501835/
https://www.ncbi.nlm.nih.gov/pubmed/36145486
http://dx.doi.org/10.3390/pathogens11091054
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author da Costa, Vanessa Duarte
Wiggers, Wilian Jean
Ivantes, Claudia Alexandra Pontes
da Fonseca, Rodrigo Jardim Monteiro
Dávila, Alberto Martín Rivera
Moreira, Otacilio C.
Ferreira, Beatriz Iandra da Silva
de Paula, Vanessa Salete
da Silva, Lucas Lima
Santos, Alanna Calheiros
Villar, Livia Melo
author_facet da Costa, Vanessa Duarte
Wiggers, Wilian Jean
Ivantes, Claudia Alexandra Pontes
da Fonseca, Rodrigo Jardim Monteiro
Dávila, Alberto Martín Rivera
Moreira, Otacilio C.
Ferreira, Beatriz Iandra da Silva
de Paula, Vanessa Salete
da Silva, Lucas Lima
Santos, Alanna Calheiros
Villar, Livia Melo
author_sort da Costa, Vanessa Duarte
collection PubMed
description The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become a major public health worldwide. Hepatic dysfunction has been seen in patients with COVID-19 and could be related to a viral cytopathic effect, an exacerbated immune reaction, or drug-induced liver damage. Currently, routine modification of immunosuppressive therapy in patients with autoimmune hepatitis (AIH) before and after SARS-CoV-2 infection remains an important topic to be discussed. However, there is little evidence about this thematic to support any recommendation. Here, we described a case report in which the use of an immunosuppressive drug by a patient with diagnosed AIH might have influenced the COVID-19 clinical course with altered laboratory hematological and biochemical parameters during infection.
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spelling pubmed-95018352022-09-24 Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient da Costa, Vanessa Duarte Wiggers, Wilian Jean Ivantes, Claudia Alexandra Pontes da Fonseca, Rodrigo Jardim Monteiro Dávila, Alberto Martín Rivera Moreira, Otacilio C. Ferreira, Beatriz Iandra da Silva de Paula, Vanessa Salete da Silva, Lucas Lima Santos, Alanna Calheiros Villar, Livia Melo Pathogens Case Report The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become a major public health worldwide. Hepatic dysfunction has been seen in patients with COVID-19 and could be related to a viral cytopathic effect, an exacerbated immune reaction, or drug-induced liver damage. Currently, routine modification of immunosuppressive therapy in patients with autoimmune hepatitis (AIH) before and after SARS-CoV-2 infection remains an important topic to be discussed. However, there is little evidence about this thematic to support any recommendation. Here, we described a case report in which the use of an immunosuppressive drug by a patient with diagnosed AIH might have influenced the COVID-19 clinical course with altered laboratory hematological and biochemical parameters during infection. MDPI 2022-09-16 /pmc/articles/PMC9501835/ /pubmed/36145486 http://dx.doi.org/10.3390/pathogens11091054 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
da Costa, Vanessa Duarte
Wiggers, Wilian Jean
Ivantes, Claudia Alexandra Pontes
da Fonseca, Rodrigo Jardim Monteiro
Dávila, Alberto Martín Rivera
Moreira, Otacilio C.
Ferreira, Beatriz Iandra da Silva
de Paula, Vanessa Salete
da Silva, Lucas Lima
Santos, Alanna Calheiros
Villar, Livia Melo
Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient
title Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient
title_full Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient
title_fullStr Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient
title_full_unstemmed Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient
title_short Characteristics of COVID-19 Infection in a Hospitalized Autoimmune Hepatitis Patient
title_sort characteristics of covid-19 infection in a hospitalized autoimmune hepatitis patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501835/
https://www.ncbi.nlm.nih.gov/pubmed/36145486
http://dx.doi.org/10.3390/pathogens11091054
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