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Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid

Dehydroabietic acid is a tricyclic diterpenoid resin acid isolated from rosin. Dehydroabietic acid and its derivatives showed lots of medical and agricultural bioactivities, such as anticancer, antibacterial, antiviral, antiulcer, insecticidal, and herbicidal activities. This review summarized the r...

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Detalles Bibliográficos
Autores principales: Hao, Meng, Xu, Jianwei, Wen, Houpeng, Du, Jiawei, Zhang, Shaoyong, Lv, Min, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501862/
https://www.ncbi.nlm.nih.gov/pubmed/36136570
http://dx.doi.org/10.3390/toxins14090632
Descripción
Sumario:Dehydroabietic acid is a tricyclic diterpenoid resin acid isolated from rosin. Dehydroabietic acid and its derivatives showed lots of medical and agricultural bioactivities, such as anticancer, antibacterial, antiviral, antiulcer, insecticidal, and herbicidal activities. This review summarized the research advances on the structural modification and total synthesis of dehydroabietic acid and its derivatives from 2015 to 2021, and analyzed the biotransformation and structure-activity relationships in order to provide a reference for the development and utilization of dehydroabietic acid and its derivatives as drugs and pesticides.