Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid

Dehydroabietic acid is a tricyclic diterpenoid resin acid isolated from rosin. Dehydroabietic acid and its derivatives showed lots of medical and agricultural bioactivities, such as anticancer, antibacterial, antiviral, antiulcer, insecticidal, and herbicidal activities. This review summarized the r...

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Autores principales: Hao, Meng, Xu, Jianwei, Wen, Houpeng, Du, Jiawei, Zhang, Shaoyong, Lv, Min, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501862/
https://www.ncbi.nlm.nih.gov/pubmed/36136570
http://dx.doi.org/10.3390/toxins14090632
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author Hao, Meng
Xu, Jianwei
Wen, Houpeng
Du, Jiawei
Zhang, Shaoyong
Lv, Min
Xu, Hui
author_facet Hao, Meng
Xu, Jianwei
Wen, Houpeng
Du, Jiawei
Zhang, Shaoyong
Lv, Min
Xu, Hui
author_sort Hao, Meng
collection PubMed
description Dehydroabietic acid is a tricyclic diterpenoid resin acid isolated from rosin. Dehydroabietic acid and its derivatives showed lots of medical and agricultural bioactivities, such as anticancer, antibacterial, antiviral, antiulcer, insecticidal, and herbicidal activities. This review summarized the research advances on the structural modification and total synthesis of dehydroabietic acid and its derivatives from 2015 to 2021, and analyzed the biotransformation and structure-activity relationships in order to provide a reference for the development and utilization of dehydroabietic acid and its derivatives as drugs and pesticides.
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spelling pubmed-95018622022-09-24 Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid Hao, Meng Xu, Jianwei Wen, Houpeng Du, Jiawei Zhang, Shaoyong Lv, Min Xu, Hui Toxins (Basel) Review Dehydroabietic acid is a tricyclic diterpenoid resin acid isolated from rosin. Dehydroabietic acid and its derivatives showed lots of medical and agricultural bioactivities, such as anticancer, antibacterial, antiviral, antiulcer, insecticidal, and herbicidal activities. This review summarized the research advances on the structural modification and total synthesis of dehydroabietic acid and its derivatives from 2015 to 2021, and analyzed the biotransformation and structure-activity relationships in order to provide a reference for the development and utilization of dehydroabietic acid and its derivatives as drugs and pesticides. MDPI 2022-09-12 /pmc/articles/PMC9501862/ /pubmed/36136570 http://dx.doi.org/10.3390/toxins14090632 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hao, Meng
Xu, Jianwei
Wen, Houpeng
Du, Jiawei
Zhang, Shaoyong
Lv, Min
Xu, Hui
Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid
title Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid
title_full Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid
title_fullStr Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid
title_full_unstemmed Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid
title_short Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid
title_sort recent advances on biological activities and structural modifications of dehydroabietic acid
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501862/
https://www.ncbi.nlm.nih.gov/pubmed/36136570
http://dx.doi.org/10.3390/toxins14090632
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