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From Bench to Cell: A Roadmap for Assessing the Bioorthogonal “Click” Reactivity of Magnetic Nanoparticles for Cell Surface Engineering

[Image: see text] In this work, we report the use of bioorthogonal chemistry, specifically the strain-promoted click azide–alkyne cycloaddition (SPAAC) for the covalent attachment of magnetic nanoparticles (MNPs) on living cell membranes. Four types of MNPs were prepared, functionalized with two dif...

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Detalles Bibliográficos
Autores principales:	Idiago-López, Javier, Moreno-Antolín, Eduardo, Eceiza, Maite, Aizpurua, Jesús M., Grazú, Valeria, de la Fuente, Jesús M., Fratila, Raluca M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501912/ https://www.ncbi.nlm.nih.gov/pubmed/35857350 http://dx.doi.org/10.1021/acs.bioconjchem.2c00230

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