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Predicting Egg Passage Adaptations to Design Better Vaccines for the H3N2 Influenza Virus

Seasonal H3N2 influenza evolves rapidly, leading to an extremely poor vaccine efficacy. Substitutions employed during vaccine production using embryonated eggs (i.e., egg passage adaptation) contribute to the poor vaccine efficacy (VE), but the evolutionary mechanism remains elusive. Using an unprec...

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Detalles Bibliográficos
Autores principales:	Liu, Yunsong, Chen, Hui, Duan, Wenyuan, Zhang, Xinyi, He, Xionglei, Nielsen, Rasmus, Ma, Liang, Zhai, Weiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501976/ https://www.ncbi.nlm.nih.gov/pubmed/36146872 http://dx.doi.org/10.3390/v14092065

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