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Human IRP1 Translocates to the Nucleus in a Cell-Specific and Iron-Dependent Manner

Iron regulatory protein 1 (IRP1) is a bifunctional protein with mutually exclusive RNA-binding or enzymatic activities that depend on the presence of a 4Fe-4S cluster. While IRP1 is a well-established cytosolic protein, work in a Drosophila model suggested that it may also exhibit nuclear localizati...

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Detalles Bibliográficos
Autores principales: Gu, Wen, Fillebeen, Carine, Pantopoulos, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502121/
https://www.ncbi.nlm.nih.gov/pubmed/36142654
http://dx.doi.org/10.3390/ijms231810740

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