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Human IRP1 Translocates to the Nucleus in a Cell-Specific and Iron-Dependent Manner
Iron regulatory protein 1 (IRP1) is a bifunctional protein with mutually exclusive RNA-binding or enzymatic activities that depend on the presence of a 4Fe-4S cluster. While IRP1 is a well-established cytosolic protein, work in a Drosophila model suggested that it may also exhibit nuclear localizati...
Autores principales: | Gu, Wen, Fillebeen, Carine, Pantopoulos, Kostas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502121/ https://www.ncbi.nlm.nih.gov/pubmed/36142654 http://dx.doi.org/10.3390/ijms231810740 |
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