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Effect of Chronic Treatment with Uridine on Cardiac Mitochondrial Dysfunction in the C57BL/6 Mouse Model of High-Fat Diet–Streptozotocin-Induced Diabetes
Long-term hyperglycemia in diabetes mellitus is associated with complex damage to cardiomyocytes and the development of mitochondrial dysfunction in the myocardium. Uridine, a pyrimidine nucleoside, plays an important role in cellular metabolism and is used to improve cardiac function. Herein, the a...
Autores principales: | Belosludtseva, Natalia V., Starinets, Vlada S., Mikheeva, Irina B., Belosludtsev, Maxim N., Dubinin, Mikhail V., Mironova, Galina D., Belosludtsev, Konstantin N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502122/ https://www.ncbi.nlm.nih.gov/pubmed/36142532 http://dx.doi.org/10.3390/ijms231810633 |
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