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Effect of Chronic Treatment with Uridine on Cardiac Mitochondrial Dysfunction in the C57BL/6 Mouse Model of High-Fat Diet–Streptozotocin-Induced Diabetes

Long-term hyperglycemia in diabetes mellitus is associated with complex damage to cardiomyocytes and the development of mitochondrial dysfunction in the myocardium. Uridine, a pyrimidine nucleoside, plays an important role in cellular metabolism and is used to improve cardiac function. Herein, the a...

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Detalles Bibliográficos
Autores principales: Belosludtseva, Natalia V., Starinets, Vlada S., Mikheeva, Irina B., Belosludtsev, Maxim N., Dubinin, Mikhail V., Mironova, Galina D., Belosludtsev, Konstantin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502122/
https://www.ncbi.nlm.nih.gov/pubmed/36142532
http://dx.doi.org/10.3390/ijms231810633

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