Cargando…

Toll-like Receptor Mediation in SARS-CoV-2: A Therapeutic Approach

The innate immune system facilitates defense mechanisms against pathogen invasion and cell damage. Toll-like receptors (TLRs) assist in the activation of the innate immune system by binding to pathogenic ligands. This leads to the generation of intracellular signaling cascades including the biosynth...

Descripción completa

Detalles Bibliográficos
Autores principales:	Manan, Abdul, Pirzada, Rameez Hassan, Haseeb, Muhammad, Choi, Sangdun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502216/ https://www.ncbi.nlm.nih.gov/pubmed/36142620 http://dx.doi.org/10.3390/ijms231810716

Ejemplares similares

Remdesivir and Ledipasvir among the FDA-Approved Antiviral Drugs Have Potential to Inhibit SARS-CoV-2 Replication
por: Pirzada, Rameez Hassan, et al.
Publicado: (2021)

Wnt Signaling in the Regulation of Immune Cell and Cancer Therapeutics
por: Haseeb, Muhammad, et al.
Publicado: (2019)

The Roles of the NLRP3 Inflammasome in Neurodegenerative and Metabolic Diseases and in Relevant Advanced Therapeutic Interventions
por: Pirzada, Rameez Hassan, et al.
Publicado: (2020)

Recent clinical trends in Toll‐like receptor targeting therapeutics
por: Anwar, Muhammad Ayaz, et al.
Publicado: (2018)

Modeling structure–activity relationships with machine learning to identify GSK3-targeted small molecules as potential COVID-19 therapeutics
por: Pirzada, Rameez Hassan, et al.
Publicado: (2023)

Negative regulatory approaches to the attenuation of Toll-like receptor signaling
por: Anwar, Muhammad Ayaz, et al.
Publicado: (2013)

A Computational Probe into the Structure and Dynamics of the Full-Length Toll-Like Receptor 3 in a Phospholipid Bilayer
por: Patra, Mahesh Chandra, et al.
Publicado: (2020)

Toll-Like Receptors and Relevant Emerging Therapeutics with Reference to Delivery Methods
por: Javaid, Nasir, et al.
Publicado: (2019)

Toll-Like Receptors as a Therapeutic Target in the Era of Immunotherapies
por: Farooq, Mariya, et al.
Publicado: (2021)

Therapeutic Applications of Nucleic Acids and Their Analogues in Toll-like Receptor Signaling
por: Gosu, Vijayakumar, et al.
Publicado: (2012)

Toll-like Receptors from the Perspective of Cancer Treatment
por: Javaid, Nasir, et al.
Publicado: (2020)

Multiple Roles of Toll-Like Receptor 4 in Colorectal Cancer
por: Yesudhas, Dhanusha, et al.
Publicado: (2014)

Therapeutic Targeting of Innate Immune Receptors Against SARS-CoV-2 Infection
por: Farooq, Mariya, et al.
Publicado: (2022)

Toll-like Receptor-Dependent Negative Effects of Opioids: A Battle between Analgesia and Hyperalgesia
por: Shah, Masaud, et al.
Publicado: (2017)

Unraveling the Tomaralimab Epitope on the Toll-like Receptor 2 via Molecular Dynamics and Deep Learning
por: Ahmad, Bilal, et al.
Publicado: (2022)

In Silico Approach to Inhibition of Signaling Pathways of Toll-Like Receptors 2 and 4 by ST2L
por: Basith, Shaherin, et al.
Publicado: (2011)

Structure and dynamic behavior of Toll‐like receptor 2 subfamily triggered by malarial glycosylphosphatidylinositols of Plasmodium falciparum
por: Durai, Prasannavenkatesh, et al.
Publicado: (2013)

Comparative Analysis of Species-Specific Ligand Recognition in Toll-Like Receptor 8 Signaling: A Hypothesis
por: Govindaraj, Rajiv Gandhi, et al.
Publicado: (2011)

Molecular Modeling-Based Evaluation of hTLR10 and Identification of Potential Ligands in Toll-Like Receptor Signaling
por: Govindaraj, Rajiv Gandhi, et al.
Publicado: (2010)

Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection
por: Mukherjee, Rukmini, et al.
Publicado: (2021)

Molecular Interactions Between Innate and Adaptive Immune Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications
por: Haseeb, Muhammad, et al.
Publicado: (2018)

Inhibition of Toll-like receptor 4 and Interleukin-1 receptor prevent SARS-CoV-2 mediated kidney injury
por: Nakazawa, Daigo, et al.
Publicado: (2023)

Computational Insight Into the Structural Organization of Full-Length Toll-Like Receptor 4 Dimer in a Model Phospholipid Bilayer
por: Patra, Mahesh Chandra, et al.
Publicado: (2018)

Role of Thioredoxin-Interacting Protein in Diseases and Its Therapeutic Outlook
por: Qayyum, Naila, et al.
Publicado: (2021)

Role of toll-like receptor 7/8 pathways in regulation of interferon response and inflammatory mediators during SARS-CoV2 infection and potential therapeutic options
por: Dyavar, Shetty Ravi, et al.
Publicado: (2021)

Current Understanding of the Innate Control of Toll-like Receptors in Response to SARS-CoV-2 Infection
por: Jung, Hi Eun, et al.
Publicado: (2021)

Association of Toll-like receptor-4 polymorphism with SARS CoV-2 infection in Kurdish Population
por: Ali, Hussein N., et al.
Publicado: (2022)

Toll-Like Receptor Signaling Pathways—Therapeutic Opportunities
por: Zhu, Jiankun, et al.
Publicado: (2010)

Role of Plant-Derived Active Constituents in Cancer Treatment and Their Mechanisms of Action
por: Khan, Abdul Waheed, et al.
Publicado: (2022)

Insight into Phosphatidylinositol-Dependent Membrane Localization of the Innate Immune Adaptor Protein Toll/Interleukin 1 Receptor Domain-Containing Adaptor Protein
por: Patra, Mahesh Chandra, et al.
Publicado: (2018)

Intravenous Administration of Toll-Like Receptor Inhibitory Peptide 1 is Effective for the Treatment of Systemic Lupus Erythematosus in a Mus musculus Model
por: Baek, Wook-Young, et al.
Publicado: (2021)

A Cell-Penetrating Peptide That Blocks Toll-Like Receptor Signaling Protects Kidneys against Ischemia-Reperfusion Injury
por: Jung, Su Woong, et al.
Publicado: (2021)

Toll-Like Receptor 2 Signaling and Current Approaches for Therapeutic Modulation in Synucleinopathies
por: Caplan, Ian F., et al.
Publicado: (2018)

Toll-like receptors and toll-like receptor-targeted immunotherapy against glioma
por: Xun, Yang, et al.
Publicado: (2021)

Toll-Like Receptors as Novel Therapeutic Targets for Ovarian Cancer
por: Muccioli, Maria, et al.
Publicado: (2012)

Toll-like receptor 2: therapeutic target for gastric carcinogenesis
por: McCormack, William, et al.
Publicado: (2012)

Toll‐like receptors in pathogenesis of neurodegenerative diseases and their therapeutic potential
por: Dabi, Yosef Tsegaye, et al.
Publicado: (2023)

A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice
por: Kwon, Hyuk-Kwon, et al.
Publicado: (2019)

Possible Link between SARS-CoV-2 Infection and Parkinson’s Disease: The Role of Toll-Like Receptor 4
por: Conte, Carmela
Publicado: (2021)

Enhancement of SARS-CoV-2 vaccine-induced immunity by a Toll-like receptor 7 agonist adjuvant
por: Li, Gen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4a1sgvk65gpphud23aqmv05pug