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Quantum-Dot-Based Iron Oxide Nanoparticles Activate the NLRP3 Inflammasome in Murine Bone Marrow-Derived Dendritic Cells

Inflammasomes are cytosolic complexes composed of a Nod-like receptor, NLR, the adaptor protein, ASC, and a proteolytic enzyme, caspase-1. Inflammasome activation leads to caspase-1 activation and promotes functional maturation of IL-1β and IL-18, two prototypical inflammatory cytokines. Besides, in...

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Detalles Bibliográficos
Autores principales: de Melo, Fernando Menegatti, Kawasaki, Karine, Sellani, Tarciso Almeida, Bonifácio, Bruno Souza, Mortara, Renato Arruda, Toma, Henrique Eisi, de Melo, Filipe Menegatti, Rodrigues, Elaine Guadelupe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502261/
https://www.ncbi.nlm.nih.gov/pubmed/36144933
http://dx.doi.org/10.3390/nano12183145