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A Metabolomics Approach for Predicting OATP1B-Type Transporter-Mediated Drug–Drug Interaction Liabilities

In recent years, various endogenous compounds have been proposed as putative biomarkers for the hepatic uptake transporters OATP1B1 and OATP1B3 that have the potential to predict transporter-mediated drug–drug interactions (DDIs). However, these compounds have often been identified from top–down str...

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Detalles Bibliográficos
Autores principales:	Li, Yang, Jin, Yan, Taheri, Hanieh, Schmidt, Keith T., Gibson, Alice A., Buck, Stefan A. J., Eisenmann, Eric D., Mathijssen, Ron H. J., Figg, William D., Baker, Sharyn D., Sparreboom, Alex, Hu, Shuiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502272/ https://www.ncbi.nlm.nih.gov/pubmed/36145680 http://dx.doi.org/10.3390/pharmaceutics14091933

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