Cargando…

Predicting Throughput and Melt Temperature in Pharmaceutical Hot Melt Extrusion

Even though hot melt extrusion (HME) is a commonly applied process in the pharmaceutical area, determination of the optimal process parameters is demanding. The goal of this study was to find a rational approach for predetermining suitable extrusion parameters, with a focus on material temperature a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gottschalk, Tobias, Özbay, Cihangir, Feuerbach, Tim, Thommes, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502425/ https://www.ncbi.nlm.nih.gov/pubmed/36145505 http://dx.doi.org/10.3390/pharmaceutics14091757

Ejemplares similares

Predicting Residence Time and Melt Temperature in Pharmaceutical Hot Melt Extrusion
por: Winck, Judith, et al.
Publicado: (2023)

Inline Determination of Residence Time Distribution in Hot-Melt-Extrusion
por: Wesholowski, Jens, et al.
Publicado: (2018)

Novel Cleaning-in-Place Strategies for Pharmaceutical Hot Melt Extrusion
por: Spoerk, Martin, et al.
Publicado: (2020)

Design and Characterization of a Screw Extrusion Hot-End for Fused Deposition Modeling
por: Feuerbach, Tim, et al.
Publicado: (2021)

A Review of Hot-Melt Extrusion: Process Technology to Pharmaceutical Products
por: Maniruzzaman, Mohammed, et al.
Publicado: (2012)

Polymer Selection for Hot-Melt Extrusion Coupled to Fused Deposition Modelling in Pharmaceutics
por: Pereira, Gabriela G., et al.
Publicado: (2020)

Hot Melt Extrusion: Highlighting Physicochemical Factors to Be Investigated While Designing and Optimizing a Hot Melt Extrusion Process
por: Censi, Roberta, et al.
Publicado: (2018)

Validation of Model-Based Melt Viscosity in Hot-Melt Extrusion Numerical Simulation
por: Bochmann, Esther S., et al.
Publicado: (2018)

Towards predicting the product quality in hot-melt extrusion: Small scale extrusion
por: Matić, Josip, et al.
Publicado: (2020)

Towards predicting the product quality in hot-melt extrusion: Pilot plant scale extrusion
por: Matić, Josip, et al.
Publicado: (2021)

Development of a Hot-Melt-Extrusion-Based Spinning Process to Produce Pharmaceutical Fibers and Yarns
por: Rosenbaum, Christoph, et al.
Publicado: (2022)

Physical Properties of Shellac Material Used for Hot Melt Extrusion with Potential Application in the Pharmaceutical Industry
por: Yan, Guangming, et al.
Publicado: (2021)

Pharmaceutical Applications of Hot-Melt Extrusion: Continuous Manufacturing, Twin-Screw Granulations, and 3D Printing
por: Maniruzzaman, Mohammed
Publicado: (2019)

Eudragit(®): A Versatile Family of Polymers for Hot Melt Extrusion and 3D Printing Processes in Pharmaceutics
por: dos Santos, Juliana, et al.
Publicado: (2021)

Hot-Melt Extrusion of the Thermo-Sensitive Peptidomimetic Drug Enalapril Maleate
por: Hoffmann, Lena, et al.
Publicado: (2022)

Hot-Melt Extrusion as an Advantageous Technology to Obtain Effervescent Drug Products
por: Lima, Ana Luiza, et al.
Publicado: (2020)

Development of Porous Polyurethane Implants Manufactured via Hot-Melt Extrusion
por: Koutsamanis, Ioannis, et al.
Publicado: (2020)

Innovations in Thermal Processing: Hot-Melt Extrusion and KinetiSol® Dispersing
por: Tan, Deck Khong, et al.
Publicado: (2020)

Preparation of Curcumin-Eudragit(®) E PO Solid Dispersions with Gradient Temperature through Hot-Melt Extrusion
por: Fan, Wenling, et al.
Publicado: (2021)

Thermal degradation of Affinisol HPMC: Optimum Processing Temperatures for Hot Melt Extrusion and 3D Printing
por: Svoboda, Roman, et al.
Publicado: (2023)

Formulation and Evaluation of Fenbendazole Extended-Release Extrudes Processed by Hot-Melt Extrusion
por: Bezerra, Gilberto S. N., et al.
Publicado: (2022)

Hot-Melt Extrusion Enhances Antioxidant Effects of Mulberry on Probiotics and Pathogenic Microorganisms
por: Go, Eun Ji, et al.
Publicado: (2022)

Influence of Carbamazepine Dihydrate on the Preparation of Amorphous Solid Dispersions by Hot Melt Extrusion
por: Ma, Xiangyu, et al.
Publicado: (2020)

An Enhanced Water Solubility and Stability of Anthocyanins in Mulberry Processed with Hot Melt Extrusion
por: Go, Eun-Ji, et al.
Publicado: (2021)

Thermoanalytical characterization of clindamycin-loaded intravitreal implants prepared by hot melt extrusion
por: Tamaddon, Lana, et al.
Publicado: (2015)

Application of hot melt extrusion to enhance the dissolution and oral bioavailability of oleanolic acid
por: Gao, Nannan, et al.
Publicado: (2017)

Drug-Eluting Sutures by Hot-Melt Extrusion: Current Trends and Future Potentials
por: Khalid, Garba M., et al.
Publicado: (2023)

Use of Terahertz-Raman Spectroscopy to Determine Solubility of the Crystalline Active Pharmaceutical Ingredient in Polymeric Matrices during Hot Melt Extrusion
por: Bordos, Ecaterina, et al.
Publicado: (2019)

The Effect of Hot-Melt Extrusion of Mulberry Leaf on the Number of Active Compounds and Antioxidant Activity
por: Kim, Hyun-Bok, et al.
Publicado: (2022)

Dissolution Enhancement in Cocoa Extract, Combining Hydrophilic Polymers through Hot-Melt Extrusion
por: Pinho, Ludmila A. G., et al.
Publicado: (2018)

Processing of Polyvinyl Acetate Phthalate in Hot-Melt Extrusion—Preparation of Amorphous Solid Dispersions
por: Monschke, Marius, et al.
Publicado: (2020)

Manganese Sulfate Nanocomposites Fabricated by Hot-Melt Extrusion for Chemodynamic Therapy of Colorectal Cancer
por: Jeong, Da In, et al.
Publicado: (2023)

Curcumin Plant for Colorectal Cancer Prediction and Prevention Using In Silico Molecular Analysis; HOT-MELT Extrusion
por: Muthu Mohamed, Jamal Moideen, et al.
Publicado: (2022)

Sustained-Release Solid Dispersion of High-Melting-Point and Insoluble Resveratrol Prepared through Hot Melt Extrusion to Improve Its Solubility and Bioavailability
por: Zhu, Wenjing, et al.
Publicado: (2021)

Advanced Pharmaceutical Applications of Hot-Melt Extrusion Coupled with Fused Deposition Modelling (FDM) 3D Printing for Personalised Drug Delivery
por: Tan, Deck Khong, et al.
Publicado: (2018)

A Miniaturized Extruder to Prototype Amorphous Solid Dispersions: Selection of Plasticizers for Hot Melt Extrusion
por: Lauer, Matthias E., et al.
Publicado: (2018)

Hot-Melt 3D Extrusion for the Fabrication of Customizable Modified-Release Solid Dosage Forms
por: Lee, Jaemin, et al.
Publicado: (2020)

The Use of Hot Melt Extrusion to Prepare a Solid Dispersion of Ibuprofen in a Polymer Matrix
por: Biedrzycka, Kinga, et al.
Publicado: (2023)

The applications of machine learning to predict the forming of chemically stable amorphous solid dispersions prepared by hot-melt extrusion
por: Jiang, Junhuang, et al.
Publicado: (2023)

Retracted: Curcumin Plant for Colorectal Cancer Prediction and Prevention Using In Silico Molecular Analysis; HOT-MELT Extrusion
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_tmt9364rrq47pb9nn1m3kd9onn