Cargando…

In Vitro Stimulation with Live SARS-CoV-2 Suggests Th17 Dominance In Virus-Specific CD4+ T Cell Response after COVID-19

The SARS-CoV-2 and influenza viruses are the main causes of human respiratory tract infections with similar disease manifestation but distinct mechanisms of immunopathology and host response to the infection. In this study, we investigated the SARS-CoV-2-specific CD4+ T cell phenotype in comparison...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kudryavtsev, Igor, Matyushenko, Victoria, Stepanova, Ekaterina, Vasilyev, Kirill, Rudenko, Larisa, Isakova-Sivak, Irina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502469/ https://www.ncbi.nlm.nih.gov/pubmed/36146622 http://dx.doi.org/10.3390/vaccines10091544

Ejemplares similares

Detection of IFNγ-Secreting CD4(+) and CD8(+) Memory T Cells in COVID-19 Convalescents after Stimulation of Peripheral Blood Mononuclear Cells with Live SARS-CoV-2
por: Matyushenko, Victoria, et al.
Publicado: (2021)

Prospects of and Barriers to the Development of Epitope-Based Vaccines against Human Metapneumovirus
por: Stepanova, Ekaterina, et al.
Publicado: (2020)

Truncation of NS1 Protein Enhances T Cell-Mediated Cross-Protection of a Live Attenuated Influenza Vaccine Virus Expressing Wild-Type Nucleoprotein
por: Prokopenko, Polina, et al.
Publicado: (2023)

Recombinant Live Attenuated Influenza Vaccine Viruses Carrying Conserved T Cell Epitopes of Human Adenoviruses Induce Functional Cytotoxic T Cell Responses and Protect Mice against both Infections
por: Isakova-Sivak, Irina, et al.
Publicado: (2020)

Safety, Immunogenicity, and Protective Efficacy of a Chimeric A/B Live Attenuated Influenza Vaccine in a Mouse Model
por: Stepanova, Ekaterina, et al.
Publicado: (2021)

Dysregulated Immune Responses in SARS-CoV-2-Infected Patients: A Comprehensive Overview
por: Kudryavtsev, Igor, et al.
Publicado: (2022)

Conserved T-cell epitopes of respiratory syncytial virus (RSV) delivered by recombinant live attenuated influenza vaccine viruses efficiently induce RSV-specific lung-localized memory T cells and augment influenza-specific resident memory T-cell responses
por: Matyushenko, Victoria, et al.
Publicado: (2020)

Genotyping assay for differentiation of wild-type and vaccine viruses in subjects immunized with live attenuated influenza vaccine
por: Matyushenko, Victoria, et al.
Publicado: (2017)

Development of a T Cell-Based COVID-19 Vaccine Using a Live Attenuated Influenza Vaccine Viral Vector
por: Isakova-Sivak, Irina, et al.
Publicado: (2022)

Universal Live-Attenuated Influenza Vaccine Candidates Expressing Multiple M2e Epitopes Protect Ferrets against a High-Dose Heterologous Virus Challenge
por: Mezhenskaya, Daria, et al.
Publicado: (2021)

A Phase 1 Randomized Placebo-Controlled Study to Assess the Safety, Immunogenicity and Genetic Stability of a New Potential Pandemic H7N9 Live Attenuated Influenza Vaccine in Healthy Adults
por: Kiseleva, Irina, et al.
Publicado: (2020)

Cross-Reactivity of SARS-CoV-2 Nucleocapsid-Binding Antibodies and Its Implication for COVID-19 Serology Tests
por: Rak, Alexandra, et al.
Publicado: (2022)

Ferristatin II Efficiently Inhibits SARS-CoV-2 Replication in Vero Cells
por: Sokolov, Alexey, et al.
Publicado: (2022)

RDE Treatment Prevents Non-Specific Detection of SARS-CoV-2- and Influenza-Specific IgG Antibodies in Heat-Inactivated Serum Samples
por: Goshina, Arina, et al.
Publicado: (2023)

A promising inactivated whole-virion SARS-CoV-2 vaccine
por: Isakova-Sivak, Irina, et al.
Publicado: (2021)

M2e-based universal influenza vaccines: a historical overview and new approaches to development
por: Mezhenskaya, Daria, et al.
Publicado: (2019)

Sequential Immunization with Universal Live Attenuated Influenza Vaccine Candidates Protects Ferrets against a High-Dose Heterologous Virus Challenge
por: Isakova-Sivak, Irina, et al.
Publicado: (2019)

A Strategy to Elicit M2e-Specific Antibodies Using a Recombinant H7N9 Live Attenuated Influenza Vaccine Expressing Multiple M2e Tandem Repeats
por: Mezhenskaya, Daria, et al.
Publicado: (2021)

Development and approval of live attenuated influenza vaccines based on Russian master donor viruses: Process challenges and success stories
por: Rudenko, Larisa, et al.
Publicado: (2016)

Contribution of Neuraminidase of Influenza Viruses to the Sensitivity to Sera Inhibitors and Reassortment Efficiency
por: Kiseleva, Irina, et al.
Publicado: (2014)

Generation and Characterization of Universal Live-Attenuated Influenza Vaccine Candidates Containing Multiple M2e Epitopes
por: Kotomina, Tatiana, et al.
Publicado: (2020)

Construction and Immunogenicity of a Novel Multivalent Vaccine Prototype Based on Conserved Influenza Virus Antigens
por: Kirsteina, Anna, et al.
Publicado: (2020)

Assessment of Immunogenic and Antigenic Properties of Recombinant Nucleocapsid Proteins of Five SARS-CoV-2 Variants in a Mouse Model
por: Rak, Alexandra, et al.
Publicado: (2023)

Two Live Attenuated Vaccines against Recent Low–and Highly Pathogenic H7N9 Influenza Viruses Are Safe and Immunogenic in Ferrets
por: Rudenko, Larisa, et al.
Publicado: (2018)

A Live Probiotic Vaccine Prototype Based on Conserved Influenza a Virus Antigens Protect Mice against Lethal Influenza Virus Infection
por: Mezhenskaya, Daria, et al.
Publicado: (2021)

Immunogenicity and Cross Protection in Mice Afforded by Pandemic H1N1 Live Attenuated Influenza Vaccine Containing Wild-Type Nucleoprotein
por: Rekstin, Andrey, et al.
Publicado: (2017)

Assessment of immune responses to H5N1 inactivated influenza vaccine among individuals previously primed with H5N2 live attenuated influenza vaccine
por: Rudenko, Larisa, et al.
Publicado: (2015)

Understanding the Variability of Certain Biological Properties of H1N1pdm09 Influenza Viruses
por: Al Farroukh, Mohammad, et al.
Publicado: (2022)

Development and Pre-Clinical Evaluation of Two LAIV Strains against Potentially Pandemic H2N2 Influenza Virus
por: Isakova-Sivak, Irina, et al.
Publicado: (2014)

Immunogenicity and Viral Shedding of Russian-Backbone, Seasonal, Trivalent, Live, Attenuated Influenza Vaccine in a Phase II, Randomized, Placebo-Controlled Trial Among Preschool-Aged Children in Urban Bangladesh
por: Lewis, Kristen D C, et al.
Publicado: (2019)

Live Attenuated Reassortant Vaccines Based on A/Leningrad/134/17/57 Master Donor Virus Against H5 Avian Influenza
por: Kiseleva, Irina, et al.
Publicado: (2017)

Tuberculosis and COVID-19 Dually Affect Human Th17 Cell Immune Response
por: Starshinova, Anna, et al.
Publicado: (2023)

Molecular mimicry of the receptor-binding domain of the SARS-CoV-2 spike protein: from the interaction of spike-specific antibodies with transferrin and lactoferrin to the antiviral effects of human recombinant lactoferrin
por: Sokolov, A. V., et al.
Publicado: (2022)

Mouse Model of IL-17-Dominant Rhinitis Using Polyinosinic-Polycytidylic Acid
por: Bae, Jun-Sang, et al.
Publicado: (2017)

The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells
por: Kim, Jiyeon S., et al.
Publicado: (2011)

MBD2 mediates Th17 cell differentiation by regulating MINK1 in Th17-dominant asthma
por: Chen, Zhifeng, et al.
Publicado: (2022)

[Image: see text] 17th SNIP Scientific Conference
Publicado: (2011)

CD11b facilitates the development of peripheral tolerance by suppressing Th17 differentiation
por: Ehirchiou, Driss, et al.
Publicado: (2007)

Cross-Protective Efficacy of Monovalent Live Influenza B Vaccines against Genetically Different Lineages of B/Victoria and B/Yamagata in Ferrets
por: Kiseleva, Irina, et al.
Publicado: (2018)

Broad cross protection by recombinant live attenuated influenza H3N2 seasonal virus expressing conserved M2 extracellular domain in a chimeric hemagglutinin
por: Park, Bo Ryoung, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dfp3d272l13jvn03it8d7a7o83