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Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach

Cancer immunotherapy moderates the immune system’s ability to fight cancer. Due to its extreme complexity, scientists are working to put together all the puzzle pieces to get a clearer picture of the immune system. Shreds of available evidence show the connection between cancer and the immune system...

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Detalles Bibliográficos
Autores principales: Mukherjee, Anirban Goutam, Wanjari, Uddesh Ramesh, Namachivayam, Arunraj, Murali, Reshma, Prabakaran, D. S., Ganesan, Raja, Renu, Kaviyarasi, Dey, Abhijit, Vellingiri, Balachandar, Ramanathan, Gnanasambandan, Doss C., George Priya, Gopalakrishnan, Abilash Valsala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502517/
https://www.ncbi.nlm.nih.gov/pubmed/36146572
http://dx.doi.org/10.3390/vaccines10091493
Descripción
Sumario:Cancer immunotherapy moderates the immune system’s ability to fight cancer. Due to its extreme complexity, scientists are working to put together all the puzzle pieces to get a clearer picture of the immune system. Shreds of available evidence show the connection between cancer and the immune system. Immune responses to tumors and lymphoid malignancies are influenced by B cells, γδT cells, NK cells, and dendritic cells (DCs). Cancer immunotherapy, which encompasses adoptive cancer therapy, monoclonal antibodies (mAbs), immune checkpoint therapy, and CART cells, has revolutionized contemporary cancer treatment. This article reviews recent developments in immune cell regulation and cancer immunotherapy. Various options are available to treat many diseases, particularly cancer, due to the progress in various immunotherapies, such as monoclonal antibodies, recombinant proteins, vaccinations (both preventative and curative), cellular immunotherapies, and cytokines.