Cargando…
Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach
Cancer immunotherapy moderates the immune system’s ability to fight cancer. Due to its extreme complexity, scientists are working to put together all the puzzle pieces to get a clearer picture of the immune system. Shreds of available evidence show the connection between cancer and the immune system...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502517/ https://www.ncbi.nlm.nih.gov/pubmed/36146572 http://dx.doi.org/10.3390/vaccines10091493 |
_version_ | 1784795725385695232 |
---|---|
author | Mukherjee, Anirban Goutam Wanjari, Uddesh Ramesh Namachivayam, Arunraj Murali, Reshma Prabakaran, D. S. Ganesan, Raja Renu, Kaviyarasi Dey, Abhijit Vellingiri, Balachandar Ramanathan, Gnanasambandan Doss C., George Priya Gopalakrishnan, Abilash Valsala |
author_facet | Mukherjee, Anirban Goutam Wanjari, Uddesh Ramesh Namachivayam, Arunraj Murali, Reshma Prabakaran, D. S. Ganesan, Raja Renu, Kaviyarasi Dey, Abhijit Vellingiri, Balachandar Ramanathan, Gnanasambandan Doss C., George Priya Gopalakrishnan, Abilash Valsala |
author_sort | Mukherjee, Anirban Goutam |
collection | PubMed |
description | Cancer immunotherapy moderates the immune system’s ability to fight cancer. Due to its extreme complexity, scientists are working to put together all the puzzle pieces to get a clearer picture of the immune system. Shreds of available evidence show the connection between cancer and the immune system. Immune responses to tumors and lymphoid malignancies are influenced by B cells, γδT cells, NK cells, and dendritic cells (DCs). Cancer immunotherapy, which encompasses adoptive cancer therapy, monoclonal antibodies (mAbs), immune checkpoint therapy, and CART cells, has revolutionized contemporary cancer treatment. This article reviews recent developments in immune cell regulation and cancer immunotherapy. Various options are available to treat many diseases, particularly cancer, due to the progress in various immunotherapies, such as monoclonal antibodies, recombinant proteins, vaccinations (both preventative and curative), cellular immunotherapies, and cytokines. |
format | Online Article Text |
id | pubmed-9502517 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95025172022-09-24 Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach Mukherjee, Anirban Goutam Wanjari, Uddesh Ramesh Namachivayam, Arunraj Murali, Reshma Prabakaran, D. S. Ganesan, Raja Renu, Kaviyarasi Dey, Abhijit Vellingiri, Balachandar Ramanathan, Gnanasambandan Doss C., George Priya Gopalakrishnan, Abilash Valsala Vaccines (Basel) Review Cancer immunotherapy moderates the immune system’s ability to fight cancer. Due to its extreme complexity, scientists are working to put together all the puzzle pieces to get a clearer picture of the immune system. Shreds of available evidence show the connection between cancer and the immune system. Immune responses to tumors and lymphoid malignancies are influenced by B cells, γδT cells, NK cells, and dendritic cells (DCs). Cancer immunotherapy, which encompasses adoptive cancer therapy, monoclonal antibodies (mAbs), immune checkpoint therapy, and CART cells, has revolutionized contemporary cancer treatment. This article reviews recent developments in immune cell regulation and cancer immunotherapy. Various options are available to treat many diseases, particularly cancer, due to the progress in various immunotherapies, such as monoclonal antibodies, recombinant proteins, vaccinations (both preventative and curative), cellular immunotherapies, and cytokines. MDPI 2022-09-07 /pmc/articles/PMC9502517/ /pubmed/36146572 http://dx.doi.org/10.3390/vaccines10091493 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Mukherjee, Anirban Goutam Wanjari, Uddesh Ramesh Namachivayam, Arunraj Murali, Reshma Prabakaran, D. S. Ganesan, Raja Renu, Kaviyarasi Dey, Abhijit Vellingiri, Balachandar Ramanathan, Gnanasambandan Doss C., George Priya Gopalakrishnan, Abilash Valsala Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach |
title | Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach |
title_full | Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach |
title_fullStr | Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach |
title_full_unstemmed | Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach |
title_short | Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach |
title_sort | role of immune cells and receptors in cancer treatment: an immunotherapeutic approach |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502517/ https://www.ncbi.nlm.nih.gov/pubmed/36146572 http://dx.doi.org/10.3390/vaccines10091493 |
work_keys_str_mv | AT mukherjeeanirbangoutam roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach AT wanjariuddeshramesh roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach AT namachivayamarunraj roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach AT muralireshma roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach AT prabakarands roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach AT ganesanraja roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach AT renukaviyarasi roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach AT deyabhijit roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach AT vellingiribalachandar roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach AT ramanathangnanasambandan roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach AT dosscgeorgepriya roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach AT gopalakrishnanabilashvalsala roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach |