Cargando…

Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach

Cancer immunotherapy moderates the immune system’s ability to fight cancer. Due to its extreme complexity, scientists are working to put together all the puzzle pieces to get a clearer picture of the immune system. Shreds of available evidence show the connection between cancer and the immune system...

Descripción completa

Detalles Bibliográficos
Autores principales: Mukherjee, Anirban Goutam, Wanjari, Uddesh Ramesh, Namachivayam, Arunraj, Murali, Reshma, Prabakaran, D. S., Ganesan, Raja, Renu, Kaviyarasi, Dey, Abhijit, Vellingiri, Balachandar, Ramanathan, Gnanasambandan, Doss C., George Priya, Gopalakrishnan, Abilash Valsala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502517/
https://www.ncbi.nlm.nih.gov/pubmed/36146572
http://dx.doi.org/10.3390/vaccines10091493
_version_ 1784795725385695232
author Mukherjee, Anirban Goutam
Wanjari, Uddesh Ramesh
Namachivayam, Arunraj
Murali, Reshma
Prabakaran, D. S.
Ganesan, Raja
Renu, Kaviyarasi
Dey, Abhijit
Vellingiri, Balachandar
Ramanathan, Gnanasambandan
Doss C., George Priya
Gopalakrishnan, Abilash Valsala
author_facet Mukherjee, Anirban Goutam
Wanjari, Uddesh Ramesh
Namachivayam, Arunraj
Murali, Reshma
Prabakaran, D. S.
Ganesan, Raja
Renu, Kaviyarasi
Dey, Abhijit
Vellingiri, Balachandar
Ramanathan, Gnanasambandan
Doss C., George Priya
Gopalakrishnan, Abilash Valsala
author_sort Mukherjee, Anirban Goutam
collection PubMed
description Cancer immunotherapy moderates the immune system’s ability to fight cancer. Due to its extreme complexity, scientists are working to put together all the puzzle pieces to get a clearer picture of the immune system. Shreds of available evidence show the connection between cancer and the immune system. Immune responses to tumors and lymphoid malignancies are influenced by B cells, γδT cells, NK cells, and dendritic cells (DCs). Cancer immunotherapy, which encompasses adoptive cancer therapy, monoclonal antibodies (mAbs), immune checkpoint therapy, and CART cells, has revolutionized contemporary cancer treatment. This article reviews recent developments in immune cell regulation and cancer immunotherapy. Various options are available to treat many diseases, particularly cancer, due to the progress in various immunotherapies, such as monoclonal antibodies, recombinant proteins, vaccinations (both preventative and curative), cellular immunotherapies, and cytokines.
format Online
Article
Text
id pubmed-9502517
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-95025172022-09-24 Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach Mukherjee, Anirban Goutam Wanjari, Uddesh Ramesh Namachivayam, Arunraj Murali, Reshma Prabakaran, D. S. Ganesan, Raja Renu, Kaviyarasi Dey, Abhijit Vellingiri, Balachandar Ramanathan, Gnanasambandan Doss C., George Priya Gopalakrishnan, Abilash Valsala Vaccines (Basel) Review Cancer immunotherapy moderates the immune system’s ability to fight cancer. Due to its extreme complexity, scientists are working to put together all the puzzle pieces to get a clearer picture of the immune system. Shreds of available evidence show the connection between cancer and the immune system. Immune responses to tumors and lymphoid malignancies are influenced by B cells, γδT cells, NK cells, and dendritic cells (DCs). Cancer immunotherapy, which encompasses adoptive cancer therapy, monoclonal antibodies (mAbs), immune checkpoint therapy, and CART cells, has revolutionized contemporary cancer treatment. This article reviews recent developments in immune cell regulation and cancer immunotherapy. Various options are available to treat many diseases, particularly cancer, due to the progress in various immunotherapies, such as monoclonal antibodies, recombinant proteins, vaccinations (both preventative and curative), cellular immunotherapies, and cytokines. MDPI 2022-09-07 /pmc/articles/PMC9502517/ /pubmed/36146572 http://dx.doi.org/10.3390/vaccines10091493 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mukherjee, Anirban Goutam
Wanjari, Uddesh Ramesh
Namachivayam, Arunraj
Murali, Reshma
Prabakaran, D. S.
Ganesan, Raja
Renu, Kaviyarasi
Dey, Abhijit
Vellingiri, Balachandar
Ramanathan, Gnanasambandan
Doss C., George Priya
Gopalakrishnan, Abilash Valsala
Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach
title Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach
title_full Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach
title_fullStr Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach
title_full_unstemmed Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach
title_short Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach
title_sort role of immune cells and receptors in cancer treatment: an immunotherapeutic approach
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502517/
https://www.ncbi.nlm.nih.gov/pubmed/36146572
http://dx.doi.org/10.3390/vaccines10091493
work_keys_str_mv AT mukherjeeanirbangoutam roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach
AT wanjariuddeshramesh roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach
AT namachivayamarunraj roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach
AT muralireshma roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach
AT prabakarands roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach
AT ganesanraja roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach
AT renukaviyarasi roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach
AT deyabhijit roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach
AT vellingiribalachandar roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach
AT ramanathangnanasambandan roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach
AT dosscgeorgepriya roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach
AT gopalakrishnanabilashvalsala roleofimmunecellsandreceptorsincancertreatmentanimmunotherapeuticapproach