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Screening and Characterization of Shark-Derived VNARs against SARS-CoV-2 Spike RBD Protein

The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein is the major target for antibody therapeutics. Shark-derived variable domains of new antigen receptors (VNARs) are the smallest antibody fragments with flexible paratopes that can recognize protein motifs inaccessible to classical ant...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Lei, Lin, Jin-Jin, Ma, Huan, Zhong, Ning, Xie, Xin-Xin, Yang, Yunru, Zheng, Peiyi, Zhang, Ling-Jing, Jin, Tengchuan, Cao, Min-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502636/
https://www.ncbi.nlm.nih.gov/pubmed/36142819
http://dx.doi.org/10.3390/ijms231810904