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Screening and Characterization of Shark-Derived VNARs against SARS-CoV-2 Spike RBD Protein
The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein is the major target for antibody therapeutics. Shark-derived variable domains of new antigen receptors (VNARs) are the smallest antibody fragments with flexible paratopes that can recognize protein motifs inaccessible to classical ant...
Autores principales: | Chen, Yu-Lei, Lin, Jin-Jin, Ma, Huan, Zhong, Ning, Xie, Xin-Xin, Yang, Yunru, Zheng, Peiyi, Zhang, Ling-Jing, Jin, Tengchuan, Cao, Min-Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502636/ https://www.ncbi.nlm.nih.gov/pubmed/36142819 http://dx.doi.org/10.3390/ijms231810904 |
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