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Interferon-Stimulated Gene 15 Knockout in Mice Impairs IFNα-Mediated Antiviral Activity

Type I interferon (IFN) plays an important role in the host defense against viral infection by inducing expression of interferon-stimulated genes (ISGs). In a previous study, we found that porcine interferon-stimulated gene 15 (ISG15) exhibited antiviral activity against PRV in vitro. To further inv...

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Detalles Bibliográficos
Autores principales: Li, Chen, He, Wen-Feng, Li, Long-Xi, Chen, Jing, Yang, Guo-Qing, Chang, Hong-Tao, Liu, Hui-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502845/
https://www.ncbi.nlm.nih.gov/pubmed/36146669
http://dx.doi.org/10.3390/v14091862