Cargando…

Interferon-Stimulated Gene 15 Knockout in Mice Impairs IFNα-Mediated Antiviral Activity

Type I interferon (IFN) plays an important role in the host defense against viral infection by inducing expression of interferon-stimulated genes (ISGs). In a previous study, we found that porcine interferon-stimulated gene 15 (ISG15) exhibited antiviral activity against PRV in vitro. To further inv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Chen, He, Wen-Feng, Li, Long-Xi, Chen, Jing, Yang, Guo-Qing, Chang, Hong-Tao, Liu, Hui-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502845/ https://www.ncbi.nlm.nih.gov/pubmed/36146669 http://dx.doi.org/10.3390/v14091862

Ejemplares similares

The Differential Antiviral Activities of Chicken Interferon α (ChIFN-α) and ChIFN-β are Related to Distinct Interferon-Stimulated Gene Expression
por: Qu, Hongren, et al.
Publicado: (2013)

Convergent Transcription of Interferon-stimulated Genes by TNF-α and IFN-α Augments Antiviral Activity against HCV and HEV
por: Wang, Wenshi, et al.
Publicado: (2016)

Species Specific Antiviral Activity of Porcine Interferon-α8 (IFNα8)
por: Kim, Eunhye, et al.
Publicado: (2017)

Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes
por: Wang, Hankun, et al.
Publicado: (2023)

Impaired Antiviral Responses to Extracellular Double-Stranded RNA and Cytosolic DNA, but Not to Interferon-α Stimulation, in TRIM56-Deficient Cells
por: Wang, Dang, et al.
Publicado: (2022)

Characteristics of oligodeoxyribonucleotides that induce interferon (IFN)-α in the pig and the phenotype of the IFN-α producing cells
por: Domeika, Kristina, et al.
Publicado: (2004)

Direct Antiviral Activity of IFN-Stimulated Genes Is Responsible for Resistance to Paramyxoviruses in ISG15-Deficient Cells
por: Holthaus, David, et al.
Publicado: (2020)

Antiviral Activity of Porcine IFN-λ3 and IFN-α against Porcine Rotavirus In Vitro
por: Deng, Lishuang, et al.
Publicado: (2022)

Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir
por: Comer, Jason E., et al.
Publicado: (2019)

Analysis of the Differential Expression and Antiviral Activity of Porcine Interferon-α In Vitro
por: Fang, Jianyu, et al.
Publicado: (2023)

Unique nonstructural proteins of Pneumonia Virus of Mice (PVM) promote degradation of interferon (IFN) pathway components and IFN-stimulated gene proteins
por: Dhar, Jayeeta, et al.
Publicado: (2016)

Interferon-stimulated genes and their antiviral effector functions
por: Schoggins, John W, et al.
Publicado: (2011)

Transcriptional Regulation of Antiviral Interferon-Stimulated Genes
por: Wang, Wenshi, et al.
Publicado: (2017)

Antiviral effects of interferon-stimulated genes in bats
por: Zhang, Dan, et al.
Publicado: (2023)

Interferon α2–Thymosin α1 Fusion Protein (IFNα2–Tα1): A Genetically Engineered Fusion Protein with Enhanced Anticancer and Antiviral Effect
por: Aslam, Muhammad Shahbaz, et al.
Publicado: (2021)

Establishment of a CRISPR/Cas9 knockout library for screening type I interferon-inducible antiviral effectors in pig cells
por: Dang, Wen, et al.
Publicado: (2022)

Interferon-Stimulated Gene 15 Conjugation Stimulates Hepatitis B Virus Production Independent of Type I Interferon Signaling Pathway In Vitro
por: Li, Yujia, et al.
Publicado: (2016)

Mitochondrial CMPK2 mediates immunomodulatory and antiviral activities through IFN-dependent and IFN-independent pathways
por: Lai, Jenn-Haung, et al.
Publicado: (2021)

Recent advances in antiviral interferon-stimulated gene biology
por: Schoggins, John W.
Publicado: (2018)

Multifaceted Antiviral Actions of Interferon-stimulated Gene Products
por: Strobl, Birgit, et al.
Publicado: (2012)

IFN-α-mediated Base Excision Repair Pathway Correlates with Antiviral Response Against Hepatitis B Virus Infection
por: Li, Yong, et al.
Publicado: (2017)

The α Chemokine, Interleukin 8, Inhibits the Antiviral Action of Interferon α
por: Khabar, Khalid S.A., et al.
Publicado: (1997)

Different antiviral effects of IFNα subtypes in a mouse model of HBV infection
por: Song, Jingjiao, et al.
Publicado: (2017)

Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes
por: Kisand, Kai, et al.
Publicado: (2008)

Decreased expression of type I (IFN-β) and type III (IFN-λ) interferons and interferon-stimulated genes in patients with chronic rhinosinusitis with and without nasal polyps
por: Hwang, Jae Woong, et al.
Publicado: (2019)

Interferon-stimulated Gene 15 (ISG15) is a trigger for tumorigenesis and metastasis of hepatocellular carcinoma
por: Li, Chong, et al.
Publicado: (2014)

Epigenetic reprogramming promotes the antiviral action of IFNα in HBV-infected cells
por: Gailhouste, Luc, et al.
Publicado: (2021)

Alpha/Beta Interferon (IFN-α/β) Signaling in Astrocytes Mediates Protection against Viral Encephalomyelitis and Regulates IFN-γ-Dependent Responses
por: Hwang, Mihyun, et al.
Publicado: (2018)

ISG15 Inhibits IFN-α-Resistant Liver Cancer Cell Growth
por: Wan, Xin-xing, et al.
Publicado: (2013)

Impairment of social behaviors in Arhgef10 knockout mice
por: Lu, Dai-Hua, et al.
Publicado: (2018)

Impaired pre-synaptic plasticity and visual responses in auxilin-knockout mice
por: Cheng, Xi, et al.
Publicado: (2023)

Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses
por: Hamming, Ole J, et al.
Publicado: (2013)

Memory Impairment in Estrogen Receptor α Knockout Mice Through Accumulation of Amyloid-β Peptides
por: Hwang, Chul Ju, et al.
Publicado: (2014)

Aberrant cell signalling in PBMCs upon IFN‐α stimulation in primary Sjögren's syndrome patients associates with type I interferon signature
por: Davies, Richard, et al.
Publicado: (2018)

Upregulated Expression of Cytotoxicity-Related Genes in IFN-γ Knockout Mice with Schistosoma japonicum Infection
por: Du, Xiaotang, et al.
Publicado: (2011)

Knockout of OsWRKY71 impairs Bph15-mediated resistance against brown planthopper in rice
por: Li, Xiaozun, et al.
Publicado: (2023)

Chicken interferome: avian interferon-stimulated genes identified by microarray and RNA-seq of primary chick embryo fibroblasts treated with a chicken type I interferon (IFN-α)
por: Giotis, Efstathios S., et al.
Publicado: (2016)

Impact of Interferon-alpha1b (IFN-α1b) on Antitumor Immune Response: An Interpretation of the Promising Therapeutic Effect of IFN-alpha1b on Melanoma
por: Liu, Yu, et al.
Publicado: (2020)

Mx Is Not Responsible for the Antiviral Activity of Interferon-α against Japanese Encephalitis Virus
por: Zhou, Jing, et al.
Publicado: (2017)

NRAV, a Long Noncoding RNA, Modulates Antiviral Responses through Suppression of Interferon-Stimulated Gene Transcription
por: Ouyang, Jing, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_37jsq73r6kleghthpidudkcpcu