Functionalized 10-Membered Aza- and Oxaenediynes through the Nicholas Reaction

The scope and limitations of the Nicholas-type cyclization for the synthesis of 10-membered benzothiophene-fused heterocyclic enediynes with different functionalities were investigated. Although the Nicholas cyclization through oxygen could be carried out in the presence of an ester group, the final...

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Detalles Bibliográficos
Autores principales: Danilkina, Natalia A., Khmelevskaya, Ekaterina A., Lyapunova, Anna G., D’yachenko, Alexander S., Bunev, Alexander S., Gasanov, Rovshan E., Gureev, Maxim A., Balova, Irina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502870/
https://www.ncbi.nlm.nih.gov/pubmed/36144808
http://dx.doi.org/10.3390/molecules27186071

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