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Hybrid-Based Wound Dressings: Combination of Synthetic and Biopolymers

Most commercialized wound dressings are polymer-based. Synthetic and natural polymers have been utilized widely for the development of wound dressings. However, the use of natural polymers is limited by their poor mechanical properties, resulting in their combination with synthetic polymers and othe...

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Autor principal: Aderibigbe, Blessing Atim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502880/
https://www.ncbi.nlm.nih.gov/pubmed/36145951
http://dx.doi.org/10.3390/polym14183806
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author Aderibigbe, Blessing Atim
author_facet Aderibigbe, Blessing Atim
author_sort Aderibigbe, Blessing Atim
collection PubMed
description Most commercialized wound dressings are polymer-based. Synthetic and natural polymers have been utilized widely for the development of wound dressings. However, the use of natural polymers is limited by their poor mechanical properties, resulting in their combination with synthetic polymers and other materials to enhance their mechanical properties. Natural polymers are mostly affordable, biocompatible, and biodegradable with promising antimicrobial activity. They have been further tailored into unique hybrid wound dressings when combined with synthetic polymers and selected biomaterials. Some important features required in an ideal wound dressing include the capability to prevent bacteria invasion, reduce odor, absorb exudates, be comfortable, facilitate easy application and removal as well as frequent changing, prevent further skin tear and irritation when applied or removed, and provide a moist environment and soothing effect, be permeable to gases, etc. The efficacy of polymers in the design of wound dressings cannot be overemphasized. This review article reports the efficacy of wound dressings prepared from a combination of synthetic and natural polymers.
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spelling pubmed-95028802022-09-24 Hybrid-Based Wound Dressings: Combination of Synthetic and Biopolymers Aderibigbe, Blessing Atim Polymers (Basel) Review Most commercialized wound dressings are polymer-based. Synthetic and natural polymers have been utilized widely for the development of wound dressings. However, the use of natural polymers is limited by their poor mechanical properties, resulting in their combination with synthetic polymers and other materials to enhance their mechanical properties. Natural polymers are mostly affordable, biocompatible, and biodegradable with promising antimicrobial activity. They have been further tailored into unique hybrid wound dressings when combined with synthetic polymers and selected biomaterials. Some important features required in an ideal wound dressing include the capability to prevent bacteria invasion, reduce odor, absorb exudates, be comfortable, facilitate easy application and removal as well as frequent changing, prevent further skin tear and irritation when applied or removed, and provide a moist environment and soothing effect, be permeable to gases, etc. The efficacy of polymers in the design of wound dressings cannot be overemphasized. This review article reports the efficacy of wound dressings prepared from a combination of synthetic and natural polymers. MDPI 2022-09-12 /pmc/articles/PMC9502880/ /pubmed/36145951 http://dx.doi.org/10.3390/polym14183806 Text en © 2022 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Aderibigbe, Blessing Atim
Hybrid-Based Wound Dressings: Combination of Synthetic and Biopolymers
title Hybrid-Based Wound Dressings: Combination of Synthetic and Biopolymers
title_full Hybrid-Based Wound Dressings: Combination of Synthetic and Biopolymers
title_fullStr Hybrid-Based Wound Dressings: Combination of Synthetic and Biopolymers
title_full_unstemmed Hybrid-Based Wound Dressings: Combination of Synthetic and Biopolymers
title_short Hybrid-Based Wound Dressings: Combination of Synthetic and Biopolymers
title_sort hybrid-based wound dressings: combination of synthetic and biopolymers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502880/
https://www.ncbi.nlm.nih.gov/pubmed/36145951
http://dx.doi.org/10.3390/polym14183806
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