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Biochemical and Hematological Markers in Workers with Chronical Exposure to Lead and Cadmium in Colombia

The aim of the present study was to find if workers chronically exposed to lead (Pb) and cadmium (Cd) presented changes in their general health and in the clinical parameters of the population under study. We carried out a cross-sectional survey in a sample of informal workers in Cartagena, Colombia...

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Autores principales: Vergara-Murillo, Fredy, Martinez-Yanez, Katiana, Fortich-Revollo, Alvaro, Paternina-Caicedo, Angel, Johnson-Restrepo, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502882/
https://www.ncbi.nlm.nih.gov/pubmed/36136488
http://dx.doi.org/10.3390/toxics10090524
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author Vergara-Murillo, Fredy
Martinez-Yanez, Katiana
Fortich-Revollo, Alvaro
Paternina-Caicedo, Angel
Johnson-Restrepo, Boris
author_facet Vergara-Murillo, Fredy
Martinez-Yanez, Katiana
Fortich-Revollo, Alvaro
Paternina-Caicedo, Angel
Johnson-Restrepo, Boris
author_sort Vergara-Murillo, Fredy
collection PubMed
description The aim of the present study was to find if workers chronically exposed to lead (Pb) and cadmium (Cd) presented changes in their general health and in the clinical parameters of the population under study. We carried out a cross-sectional survey in a sample of informal workers in Cartagena, Colombia. The population under study was composed of male informal workers (≥18 years of age), with experience in their job, selected from occupational settings with potential exposure to Pb and Cd (i.e., mechanics, battery and garbage recyclers, and welders). The median age was 45 years (interquartile range (IQR), 33–53). The median blood Pb level (BLL) was 2 μg/dL (IQR, 0.76–6.22), and the median of blood Cd level (BCL) was 1.22 μg/L (IQR, 0.33–2.01). The study found that 33% of high exposure jobs with BLL > 5 μg/dL (n = 57), whereas in ‘control’ workers, this was 15.3% (n = 9). The highest BLLs were found in battery recyclers (82.1%; n = 23), followed by mechanics (37.3%, n = 22). In the logistic regression model adjusted by age, time on the job, smoking and elevated BCL and BLL increased 3.2 times (95% CI, 1.1–9.7) in mechanics and 29.6 times (95% CI, 7.2–145.6) in battery recyclers. This study found negative changes in the health of workers with higher chronic exposure to lead in Cartagena, Colombia.
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spelling pubmed-95028822022-09-24 Biochemical and Hematological Markers in Workers with Chronical Exposure to Lead and Cadmium in Colombia Vergara-Murillo, Fredy Martinez-Yanez, Katiana Fortich-Revollo, Alvaro Paternina-Caicedo, Angel Johnson-Restrepo, Boris Toxics Article The aim of the present study was to find if workers chronically exposed to lead (Pb) and cadmium (Cd) presented changes in their general health and in the clinical parameters of the population under study. We carried out a cross-sectional survey in a sample of informal workers in Cartagena, Colombia. The population under study was composed of male informal workers (≥18 years of age), with experience in their job, selected from occupational settings with potential exposure to Pb and Cd (i.e., mechanics, battery and garbage recyclers, and welders). The median age was 45 years (interquartile range (IQR), 33–53). The median blood Pb level (BLL) was 2 μg/dL (IQR, 0.76–6.22), and the median of blood Cd level (BCL) was 1.22 μg/L (IQR, 0.33–2.01). The study found that 33% of high exposure jobs with BLL > 5 μg/dL (n = 57), whereas in ‘control’ workers, this was 15.3% (n = 9). The highest BLLs were found in battery recyclers (82.1%; n = 23), followed by mechanics (37.3%, n = 22). In the logistic regression model adjusted by age, time on the job, smoking and elevated BCL and BLL increased 3.2 times (95% CI, 1.1–9.7) in mechanics and 29.6 times (95% CI, 7.2–145.6) in battery recyclers. This study found negative changes in the health of workers with higher chronic exposure to lead in Cartagena, Colombia. MDPI 2022-09-01 /pmc/articles/PMC9502882/ /pubmed/36136488 http://dx.doi.org/10.3390/toxics10090524 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Vergara-Murillo, Fredy
Martinez-Yanez, Katiana
Fortich-Revollo, Alvaro
Paternina-Caicedo, Angel
Johnson-Restrepo, Boris
Biochemical and Hematological Markers in Workers with Chronical Exposure to Lead and Cadmium in Colombia
title Biochemical and Hematological Markers in Workers with Chronical Exposure to Lead and Cadmium in Colombia
title_full Biochemical and Hematological Markers in Workers with Chronical Exposure to Lead and Cadmium in Colombia
title_fullStr Biochemical and Hematological Markers in Workers with Chronical Exposure to Lead and Cadmium in Colombia
title_full_unstemmed Biochemical and Hematological Markers in Workers with Chronical Exposure to Lead and Cadmium in Colombia
title_short Biochemical and Hematological Markers in Workers with Chronical Exposure to Lead and Cadmium in Colombia
title_sort biochemical and hematological markers in workers with chronical exposure to lead and cadmium in colombia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502882/
https://www.ncbi.nlm.nih.gov/pubmed/36136488
http://dx.doi.org/10.3390/toxics10090524
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