Cargando…

Phytoestrogen Coumestrol Selectively Inhibits Monoamine Oxidase-A and Amyloid β Self-Aggregation

Pueraria lobata leaves contain a variety of phytoestrogens, including flavonoids, isoflavonoids, and coumestan derivatives. In this study, we aimed to identify the active ingredients of P. lobata leaves and to elucidate their function in monoamine oxidase (MAO) activation and Aβ self-aggregation usi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seong, Su Hui, Kim, Bo-Ram, Cho, Myoung Lae, Kim, Tae-Su, Im, Sua, Han, Seahee, Jeong, Jin-Woo, Jung, Hyun Ah, Choi, Jae Sue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502896/ https://www.ncbi.nlm.nih.gov/pubmed/36145197 http://dx.doi.org/10.3390/nu14183822

Ejemplares similares

Comprehensive RNA sequencing and co-expression network analysis to complete the biosynthetic pathway of coumestrol, a phytoestrogen
por: Ha, Jungmin, et al.
Publicado: (2019)

Coumestrol Epigenetically Suppresses Cancer Cell Proliferation: Coumestrol Is a Natural Haspin Kinase Inhibitor
por: Kim, Jong-Eun, et al.
Publicado: (2017)

Comparative Evaluation of the Antioxidant and Anti-Alzheimer’s Disease Potential of Coumestrol and Puerarol Isolated from Pueraria lobata Using Molecular Modeling Studies
por: Koirala, Prashamsa, et al.
Publicado: (2018)

Mass Biosynthesis of Coumestrol Derivatives and Their Isomers via Soybean Adventitious Root Cultivation in Bioreactors
por: Lee, Eun Jung, et al.
Publicado: (2022)

Rubrofusarin as a Dual Protein Tyrosine Phosphate 1B and Human Monoamine Oxidase-A Inhibitor: An in Vitro and in Silico Study
por: Paudel, Pradeep, et al.
Publicado: (2019)

Inhibition of Butyrylcholinesterase and Human Monoamine Oxidase-B by the Coumarin Glycyrol and Liquiritigenin Isolated from Glycyrrhiza uralensis
por: Jeong, Geum Seok, et al.
Publicado: (2020)

In Vitro and in Silico Human Monoamine Oxidase Inhibitory Potential of Anthraquinones, Naphthopyrones, and Naphthalenic Lactones from Cassia obtusifolia Linn Seeds
por: Paudel, Pradeep, et al.
Publicado: (2019)

In Vitro Human Monoamine Oxidase Inhibition and Human Dopamine D(4) Receptor Antagonist Effect of Natural Flavonoids for Neuroprotection
por: Paudel, Pradeep, et al.
Publicado: (2023)

Emodin Derivatives as Multi-Target-Directed Ligands Inhibiting Monoamine Oxidase and Antagonizing Vasopressin V(1A) Receptors
por: Paudel, Pradeep, et al.
Publicado: (2020)

Monoamine Oxidase-A Occupancy by Moclobemide and Phenelzine: Implications for the Development of Monoamine Oxidase Inhibitors
por: Chiuccariello, Lina, et al.
Publicado: (2015)

Lactational coumestrol exposure increases ovarian apoptosis in adult rats
por: Moon, Hyun-Ju, et al.
Publicado: (2009)

Novel Diels–Alder Type Adducts from Morus alba Root Bark Targeting Human Monoamine Oxidase and Dopaminergic Receptors for the Management of Neurodegenerative Diseases
por: Paudel, Pradeep, et al.
Publicado: (2019)

Effective methods for increasing coumestrol in soybean sprouts
por: Ohta, Tomoe, et al.
Publicado: (2021)

Probing Multi-Target Action of Phlorotannins as New Monoamine Oxidase Inhibitors and Dopaminergic Receptor Modulators with the Potential for Treatment of Neuronal Disorders
por: Seong, Su Hui, et al.
Publicado: (2019)

Isoliquiritigenin, a potent human monoamine oxidase inhibitor, modulates dopamine D(1), D(3), and vasopressin V(1A) receptors
por: Prajapati, Ritu, et al.
Publicado: (2021)

ABUSE OF MONOAMINE OXIDASE INHIBITORS
por: Ananth, Jambur, et al.
Publicado: (1995)

Monoamine Oxidase Inhibition by Major Tanshinones from Salvia miltiorrhiza and Selective Muscarinic Acetylcholine M(4) Receptor Antagonism by Tanshinone I
por: Prajapati, Ritu, et al.
Publicado: (2021)

Neuroprotective Function of Rasagiline and Selegiline, Inhibitors of Type B Monoamine Oxidase, and Role of Monoamine Oxidases in Synucleinopathies
por: Naoi, Makoto, et al.
Publicado: (2022)

Amphetamine Derivatives as Monoamine Oxidase Inhibitors
por: Reyes-Parada, Miguel, et al.
Publicado: (2020)

Parameters for Irreversible Inactivation of Monoamine Oxidase
por: Ramsay, Rona R., et al.
Publicado: (2020)

Quinoline-Malononitrile-Based Aggregation-Induced Emission Probe for Monoamine Oxidase Detection in Living Cells
por: Duangkamol, Chuthamat, et al.
Publicado: (2023)

New Monocyclic Terpenoid Lactones from a Brown Algae Sargassum macrocarpum as Monoamine Oxidase Inhibitors
por: Kwon, Jaeyoung, et al.
Publicado: (2022)

A Potential Role of Coumestrol in Soybean Leaf Senescence and Its Interaction With Phytohormones
por: Mun, Bong-Gyu, et al.
Publicado: (2021)

3-Coumaranone derivatives as inhibitors of monoamine oxidase
por: Van Dyk, Adriaan S, et al.
Publicado: (2015)

Monoamine Oxidase B in Renal Cell Carcinoma
por: Hodorová, Ingrid, et al.
Publicado: (2018)

Cardiac monoamine oxidases: at the heart of mitochondrial dysfunction
por: Mialet-Perez, Jeanne, et al.
Publicado: (2020)

Medicarpin and Homopterocarpin Isolated from Canavalia lineata as Potent and Competitive Reversible Inhibitors of Human Monoamine Oxidase-B
por: Oh, Jong Min, et al.
Publicado: (2022)

Effects of coumestrol on estrogen receptor function and uterine growth in ovariectomized rats.
por: Markaverich, B M, et al.
Publicado: (1995)

Estrogenic Activity of Coumestrol, DDT, and TCDD in Human Cervical Cancer Cells
por: Ndebele, Kenneth, et al.
Publicado: (2010)

Monoamine oxidase A is down-regulated in EBV-associated nasopharyngeal carcinoma
por: Lee, Hui Min, et al.
Publicado: (2020)

Monoamine Oxidase and Dopamine β-Hydroxylase Inhibitors from the Fruits of Gardenia jasminoides
por: Kim, Ji Ho, et al.
Publicado: (2012)

Smoking Related Diseases: The Central Role of Monoamine Oxidase
por: Rendu, Francine, et al.
Publicado: (2011)

Androgen receptor and monoamine oxidase polymorphism in wild bonobos
por: Garai, Cintia, et al.
Publicado: (2014)

Inhibition of Monoamine Oxidase by Stilbenes from Rheum palmatum
por: Wei, Bo, et al.
Publicado: (2016)

Mitochondrial Monoamine Oxidase: Another Player in Pulmonary Hypertension?
por: Sommer, Natascha, et al.
Publicado: (2021)

Recent advances on the role of monoamine oxidases in cardiac pathophysiology
por: Kaludercic, Nina, et al.
Publicado: (2023)

Protective Effects of Coumestrol on Metabolic Dysfunction and Its Estrogen Receptor-Mediated Action in Ovariectomized Mice
por: Park, Song, et al.
Publicado: (2023)

Rosmarinic acid suppresses Alzheimer’s disease development by reducing amyloid β aggregation by increasing monoamine secretion
por: Hase, Tomoki, et al.
Publicado: (2019)

Effect of Alkaloids Isolated from Phyllodium pulchellum on Monoamine Levels and Monoamine Oxidase Activity in Rat Brain
por: Cai, Lu, et al.
Publicado: (2016)

Halogenated Coumarin–Chalcones as Multifunctional Monoamine Oxidase-B and Butyrylcholinesterase Inhibitors
por: Rehuman, Nisha Abdul, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2b9tbrrth5mrdlmvj4ae1116f0