Disruption of grin2B, an ASD-associated gene, produces social deficits in zebrafish

BACKGROUND: Autism spectrum disorder (ASD), like many neurodevelopmental disorders, has complex and varied etiologies. Advances in genome sequencing have identified multiple candidate genes associated with ASD, including dozens of missense and nonsense mutations in the NMDAR subunit GluN2B, encoded...

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Detalles Bibliográficos
Autores principales: Zoodsma, Josiah D., Keegan, Emma J., Moody, Gabrielle R., Bhandiwad, Ashwin A., Napoli, Amalia J., Burgess, Harold A., Wollmuth, Lonnie P., Sirotkin, Howard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502958/
https://www.ncbi.nlm.nih.gov/pubmed/36138431
http://dx.doi.org/10.1186/s13229-022-00516-3

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