Spreading Depolarization as a Therapeutic Target in Severe Ischemic Stroke: Physiological and Pharmacological Strategies

Background: Spreading depolarization (SD) occurs nearly ubiquitously in malignant hemispheric stroke (MHS) and is strongly implicated in edema progression and lesion expansion. Due to this high burden of SD after infarct, it is of great interest whether SD in MHS patients can be mitigated by physiol...

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Detalles Bibliográficos
Autores principales: Chau, Lily, Davis, Herbert T., Jones, Thomas, Greene-Chandos, Diana, Torbey, Michel, Shuttleworth, C. William, Carlson, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502975/
https://www.ncbi.nlm.nih.gov/pubmed/36143232
http://dx.doi.org/10.3390/jpm12091447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502975/
https://www.ncbi.nlm.nih.gov/pubmed/36143232
http://dx.doi.org/10.3390/jpm12091447

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