Cargando…
Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications
Diabetes mellitus, a metabolic disease mainly characterized by hyperglycemia, is becoming a serious social health problem worldwide with growing prevalence. Many natural compounds have been found to be effective in the prevention and treatment of diabetes, with negligible toxic effects. Ferulic acid...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503003/ https://www.ncbi.nlm.nih.gov/pubmed/36144745 http://dx.doi.org/10.3390/molecules27186010 |
_version_ | 1784795855958573056 |
---|---|
author | Li, Xu Wu, Jingxian Xu, Fanxing Chu, Chun Li, Xiang Shi, Xinyi Zheng, Wen Wang, Zhenzhong Jia, Ying Xiao, Wei |
author_facet | Li, Xu Wu, Jingxian Xu, Fanxing Chu, Chun Li, Xiang Shi, Xinyi Zheng, Wen Wang, Zhenzhong Jia, Ying Xiao, Wei |
author_sort | Li, Xu |
collection | PubMed |
description | Diabetes mellitus, a metabolic disease mainly characterized by hyperglycemia, is becoming a serious social health problem worldwide with growing prevalence. Many natural compounds have been found to be effective in the prevention and treatment of diabetes, with negligible toxic effects. Ferulic acid (FA), a phenolic compound commonly found in medicinal herbs and the daily diet, was proved to have several pharmacological effects such as antihyperglycemic, antihyperlipidemic and antioxidant actions, which are beneficial to the management of diabetes and its complications. Data from PubMed, EM-BASE, Web of Science and CNKI were searched with the keywords ferulic acid and diabetes mellitus. Finally, 28 articles were identified after literature screening, and the research progress of FA for the management of DM and its complications was summarized in the review, in order to provide references for further research and medical applications of FA. |
format | Online Article Text |
id | pubmed-9503003 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95030032022-09-24 Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications Li, Xu Wu, Jingxian Xu, Fanxing Chu, Chun Li, Xiang Shi, Xinyi Zheng, Wen Wang, Zhenzhong Jia, Ying Xiao, Wei Molecules Review Diabetes mellitus, a metabolic disease mainly characterized by hyperglycemia, is becoming a serious social health problem worldwide with growing prevalence. Many natural compounds have been found to be effective in the prevention and treatment of diabetes, with negligible toxic effects. Ferulic acid (FA), a phenolic compound commonly found in medicinal herbs and the daily diet, was proved to have several pharmacological effects such as antihyperglycemic, antihyperlipidemic and antioxidant actions, which are beneficial to the management of diabetes and its complications. Data from PubMed, EM-BASE, Web of Science and CNKI were searched with the keywords ferulic acid and diabetes mellitus. Finally, 28 articles were identified after literature screening, and the research progress of FA for the management of DM and its complications was summarized in the review, in order to provide references for further research and medical applications of FA. MDPI 2022-09-15 /pmc/articles/PMC9503003/ /pubmed/36144745 http://dx.doi.org/10.3390/molecules27186010 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Li, Xu Wu, Jingxian Xu, Fanxing Chu, Chun Li, Xiang Shi, Xinyi Zheng, Wen Wang, Zhenzhong Jia, Ying Xiao, Wei Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications |
title | Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications |
title_full | Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications |
title_fullStr | Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications |
title_full_unstemmed | Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications |
title_short | Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications |
title_sort | use of ferulic acid in the management of diabetes mellitus and its complications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503003/ https://www.ncbi.nlm.nih.gov/pubmed/36144745 http://dx.doi.org/10.3390/molecules27186010 |
work_keys_str_mv | AT lixu useofferulicacidinthemanagementofdiabetesmellitusanditscomplications AT wujingxian useofferulicacidinthemanagementofdiabetesmellitusanditscomplications AT xufanxing useofferulicacidinthemanagementofdiabetesmellitusanditscomplications AT chuchun useofferulicacidinthemanagementofdiabetesmellitusanditscomplications AT lixiang useofferulicacidinthemanagementofdiabetesmellitusanditscomplications AT shixinyi useofferulicacidinthemanagementofdiabetesmellitusanditscomplications AT zhengwen useofferulicacidinthemanagementofdiabetesmellitusanditscomplications AT wangzhenzhong useofferulicacidinthemanagementofdiabetesmellitusanditscomplications AT jiaying useofferulicacidinthemanagementofdiabetesmellitusanditscomplications AT xiaowei useofferulicacidinthemanagementofdiabetesmellitusanditscomplications |