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Muscle-in-Vein Conduits for the Treatment of Symptomatic Neuroma of Sensory Digital Nerves

Background: Considering the debilitating burden of neuroma resulting in a significant loss of function and excruciating pain, the use of muscle-in-vein conduits (MVCs) for the reconstruction of painful neuroma of sensory nerves of the fingers was assessed. Methods: We retrospectively analyzed 10 pat...

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Autores principales: Ederer, Ines Ana, Kolbenschlag, Jonas, Daigeler, Adrien, Wahler, Theodora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503054/
https://www.ncbi.nlm.nih.gov/pubmed/36143300
http://dx.doi.org/10.3390/jpm12091514
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author Ederer, Ines Ana
Kolbenschlag, Jonas
Daigeler, Adrien
Wahler, Theodora
author_facet Ederer, Ines Ana
Kolbenschlag, Jonas
Daigeler, Adrien
Wahler, Theodora
author_sort Ederer, Ines Ana
collection PubMed
description Background: Considering the debilitating burden of neuroma resulting in a significant loss of function and excruciating pain, the use of muscle-in-vein conduits (MVCs) for the reconstruction of painful neuroma of sensory nerves of the fingers was assessed. Methods: We retrospectively analyzed 10 patients who underwent secondary digital nerve repair by MVCs. The recovery of sensibility was evaluated by static and moving two-point discrimination (2PDs, 2PDm) and Semmes-Weinstein monofilament testing (SWM). The minimum follow-up was set 12 months after the operation. Results: The median period between trauma and nerve repair was 13.4 weeks (IQR 53.5). After neuroma resection, defects ranged from 10–35 mm (mean 17.7 mm, SD 0.75). The successful recovery of sensibility was achieved in 90% of patients after a median follow-up of 27.0 months (IQR 31.00). The mean 2PDs and 2PDm was 8.1 mm (SD 3.52) and 5.2 mm (SD 2.27), respectively. Assessment by SWM resulted in a mean value of 3.54 (SD 0.69). Reduction in pain was achieved among all patients; eight patients reported the complete relief of neuropathic pain. There was no recurrence of neuroma in any patient. Conclusions: Muscle-in-vein conduits provide an effective treatment for painful neuroma of digital nerves, resulting in satisfactory restoration of sensory function and relief of pain.
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spelling pubmed-95030542022-09-24 Muscle-in-Vein Conduits for the Treatment of Symptomatic Neuroma of Sensory Digital Nerves Ederer, Ines Ana Kolbenschlag, Jonas Daigeler, Adrien Wahler, Theodora J Pers Med Article Background: Considering the debilitating burden of neuroma resulting in a significant loss of function and excruciating pain, the use of muscle-in-vein conduits (MVCs) for the reconstruction of painful neuroma of sensory nerves of the fingers was assessed. Methods: We retrospectively analyzed 10 patients who underwent secondary digital nerve repair by MVCs. The recovery of sensibility was evaluated by static and moving two-point discrimination (2PDs, 2PDm) and Semmes-Weinstein monofilament testing (SWM). The minimum follow-up was set 12 months after the operation. Results: The median period between trauma and nerve repair was 13.4 weeks (IQR 53.5). After neuroma resection, defects ranged from 10–35 mm (mean 17.7 mm, SD 0.75). The successful recovery of sensibility was achieved in 90% of patients after a median follow-up of 27.0 months (IQR 31.00). The mean 2PDs and 2PDm was 8.1 mm (SD 3.52) and 5.2 mm (SD 2.27), respectively. Assessment by SWM resulted in a mean value of 3.54 (SD 0.69). Reduction in pain was achieved among all patients; eight patients reported the complete relief of neuropathic pain. There was no recurrence of neuroma in any patient. Conclusions: Muscle-in-vein conduits provide an effective treatment for painful neuroma of digital nerves, resulting in satisfactory restoration of sensory function and relief of pain. MDPI 2022-09-15 /pmc/articles/PMC9503054/ /pubmed/36143300 http://dx.doi.org/10.3390/jpm12091514 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ederer, Ines Ana
Kolbenschlag, Jonas
Daigeler, Adrien
Wahler, Theodora
Muscle-in-Vein Conduits for the Treatment of Symptomatic Neuroma of Sensory Digital Nerves
title Muscle-in-Vein Conduits for the Treatment of Symptomatic Neuroma of Sensory Digital Nerves
title_full Muscle-in-Vein Conduits for the Treatment of Symptomatic Neuroma of Sensory Digital Nerves
title_fullStr Muscle-in-Vein Conduits for the Treatment of Symptomatic Neuroma of Sensory Digital Nerves
title_full_unstemmed Muscle-in-Vein Conduits for the Treatment of Symptomatic Neuroma of Sensory Digital Nerves
title_short Muscle-in-Vein Conduits for the Treatment of Symptomatic Neuroma of Sensory Digital Nerves
title_sort muscle-in-vein conduits for the treatment of symptomatic neuroma of sensory digital nerves
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503054/
https://www.ncbi.nlm.nih.gov/pubmed/36143300
http://dx.doi.org/10.3390/jpm12091514
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