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L-Serine-Modified Poly-L-Lysine as a Biodegradable Kidney-Targeted Drug Carrier for the Efficient Radionuclide Therapy of Renal Cell Carcinoma

In the present study, L-serine (Ser)-modified poly-L-lysine (PLL) was synthesized to develop a biodegradable, kidney-targeted drug carrier for efficient radionuclide therapy in renal cell carcinoma (RCC). Ser-PLL was labeled with (111)In/(90)Y via diethylenetriaminepentaacetic acid (DTPA) chelation...

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Detalles Bibliográficos
Autores principales: Katsumi, Hidemasa, Kitada, Sho, Yasuoka, Shintaro, Takashima, Rie, Imanishi, Tomoki, Tanaka, Rina, Matsuura, Satoru, Kimura, Hiroyuki, Kawashima, Hidekazu, Morishita, Masaki, Yamamoto, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503061/
https://www.ncbi.nlm.nih.gov/pubmed/36145694
http://dx.doi.org/10.3390/pharmaceutics14091946