Cargando…

L-Serine-Modified Poly-L-Lysine as a Biodegradable Kidney-Targeted Drug Carrier for the Efficient Radionuclide Therapy of Renal Cell Carcinoma

In the present study, L-serine (Ser)-modified poly-L-lysine (PLL) was synthesized to develop a biodegradable, kidney-targeted drug carrier for efficient radionuclide therapy in renal cell carcinoma (RCC). Ser-PLL was labeled with (111)In/(90)Y via diethylenetriaminepentaacetic acid (DTPA) chelation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Katsumi, Hidemasa, Kitada, Sho, Yasuoka, Shintaro, Takashima, Rie, Imanishi, Tomoki, Tanaka, Rina, Matsuura, Satoru, Kimura, Hiroyuki, Kawashima, Hidekazu, Morishita, Masaki, Yamamoto, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503061/ https://www.ncbi.nlm.nih.gov/pubmed/36145694 http://dx.doi.org/10.3390/pharmaceutics14091946

Ejemplares similares

l-Cysteine and l-Serine Modified Dendrimer with Multiple Reduced Thiols as a Kidney-Targeting Reactive Oxygen Species Scavenger to Prevent Renal Ischemia/Reperfusion Injury
por: Matsuura, Satoru, et al.
Publicado: (2018)

Heat Capacities of L-Cysteine, L-Serine, L-Threonine, L-Lysine, and L-Methionine
por: Pokorný, Václav, et al.
Publicado: (2023)

Structural Basis for Recognition of L-lysine, L-ornithine, and L-2,4-diamino Butyric Acid by Lysine Cyclodeaminase
por: Min, Kyungjin, et al.
Publicado: (2018)

Improving l-serine formation by Escherichia coli by reduced uptake of produced l-serine
por: Wang, Chenyang, et al.
Publicado: (2020)

Bioavailability of l-lysine sulfate relative to l-lysine HCl for growing–finishing pigs
por: Li, Qingyun, et al.
Publicado: (2019)

Modulating the poly-l-lysine structure through the control of the protonation–deprotonation state of l-lysine
por: Stagi, Luigi, et al.
Publicado: (2022)

Assessment of the Efficacy of L-Lysine Sulfate vis-à-vis L-Lysine Hydrochloride as Sources of Supplemental Lysine in Broiler Chickens
por: Bahadur, Vijay, et al.
Publicado: (2010)

Development of Nontoxic Biodegradable Polyurethanes Based on Polyhydroxyalkanoate and L-lysine Diisocyanate with Improved Mechanical Properties as New Elastomers Scaffolds
por: Wang, Cai, et al.
Publicado: (2019)

Lysine, Lysine-Rich, Serine, and Serine-Rich Proteins: Link Between Metabolism, Development, and Abiotic Stress Tolerance and the Role of ncRNAs in Their Regulation
por: Kishor, P. B. Kavi, et al.
Publicado: (2020)

Data describing the swelling behavior and cytocompatibility of biodegradable polyelectrolyte hydrogels incorporating poly(L-lysine) for applications in cartilage tissue engineering
por: Lam, Johnny, et al.
Publicado: (2016)

NIPAm-Based Modification of Poly(L-lysine): A pH-Dependent LCST-Type Thermo-Responsive Biodegradable Polymer
por: Stamou, Aggeliki, et al.
Publicado: (2022)

Photoinduced Processes in Lysine-Tryptophan-Lysine Tripeptide with L and D Tryptophan
por: Ageeva, Aleksandra A., et al.
Publicado: (2023)

Engineering photosynthetic production of L-lysine
por: Korosh, Travis C., et al.
Publicado: (2017)

Enzymatic production of 5-aminovalerate from l-lysine using l-lysine monooxygenase and 5-aminovaleramide amidohydrolase
por: Liu, Pan, et al.
Publicado: (2014)

Recent Advances in Epsilon-Poly-L-Lysine and L-Lysine-Based Dendrimer Synthesis, Modification, and Biomedical Applications
por: Chen, Sijin, et al.
Publicado: (2021)

l-Serine methyl ester hydrochloride
por: Schouten, Arie, et al.
Publicado: (2009)

Effects of L-serine ingestion on human sleep
por: Ito, Yukihiko, et al.
Publicado: (2014)

Formal synthesis of (+)-lactacystin from l-serine
por: Bulman Page, Philip C., et al.
Publicado: (2019)

L-serine: Neurological Implications and Therapeutic Potential
por: Phone Myint, Soe Maung Maung, et al.
Publicado: (2023)

Plasma L-Carnitine and L-Lysine Concentrations in HIV-Infected Patients
por: Butorov, Evgeny V.
Publicado: (2017)

Rubidium pentaaqua(l-serine)cobalt(II) hexahydrogenhexamolybdocobaltate(III) l-serine monosolvate decahydrate
por: Iijima, Jun, et al.
Publicado: (2013)

Artificial Radionuclides Database in the Pacific Ocean: HAM Database
por: Aoyama, Michio, et al.
Publicado: (2004)

Suppression of acute pancreatitis by L-lysine in mice
por: Al-Malki, Abdulrahman L.
Publicado: (2015)

Anticyanobacterial effect of l-lysine on Microcystis aeruginosa
por: Tian, Lili, et al.
Publicado: (2018)

Synthesis and Biodegradation Test of a New Polyether Polyurethane Foam Produced from PEG 400, (L)-Lysine Ethyl Ester Diisocyanate (L-LDI) and Bis-hydroxymethyl Furan (BHMF)
por: Olivito, Fabrizio, et al.
Publicado: (2023)

Safety of concentrated l‐lysine (base), l‐lysine monohydrochloride and l‐lysine sulfate produced using different strains of Corynebacterium glutamicum for all animal species based on a dossier submitted by FEFANA asbl
por: Bampidis, Vasileios, et al.
Publicado: (2019)

In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L
por: Morishita, Masayo, et al.
Publicado: (2014)

Synthesis of L-Ornithine- and L-Glutamine-Linked PLGAs as Biodegradable Polymers
por: Taşkor Önel, Gülce
Publicado: (2023)

Amino acids, L-Cysteine and L-Methionine, Attenuate Activation of Rat Stellate Cells in Primary Culture
por: Matsui, Hiroko, et al.
Publicado: (2004)

High-Level Conversion of l-lysine into Cadaverine by Escherichia coli Whole Cell Biocatalyst Expressing Hafnia alvei l-lysine Decarboxylase
por: Kim, Hee Taek, et al.
Publicado: (2019)

Enhanced ε-Poly-L-Lysine Production by the Synergistic Effect of ε-Poly-L-Lysine Synthetase Overexpression and Citrate in Streptomyces albulus
por: Wang, Aixia, et al.
Publicado: (2020)

Effects of l-Serine on Macrolide Resistance in Streptococcus suis
por: Wu, Tong, et al.
Publicado: (2022)

Separation and detection of D-/L-serine by conventional HPLC
por: Shikanai, Hiroki, et al.
Publicado: (2022)

Structural basis of enzyme activity regulation by the propeptide of l-lysine α-oxidase precursor from Trichoderma viride
por: Kitagawa, Masaki, et al.
Publicado: (2021)

Evaluation of transgene expression characteristics and DNA vaccination against melanoma metastasis of an intravenously injected ternary complex with biodegradable dendrigraft poly-L-lysine in mice
por: Kodama, Yukinobu, et al.
Publicado: (2021)

Antinociceptive Effect of Rat D-Serine Racemase Inhibitors, L-Serine-O-Sulfate, and L-Erythro-3-Hydroxyaspartate in an Arthritic Pain Model
por: Laurido, Claudio, et al.
Publicado: (2012)

l-Serine Biosensor-Controlled Fermentative Production of l-Tryptophan Derivatives by Corynebacterium glutamicum
por: Ferrer, Lenny, et al.
Publicado: (2022)

A study on L-threonine and L-serine uptake in Escherichia coli K-12
por: Khozov, Andrey A., et al.
Publicado: (2023)

Cadaverine Production From L-Lysine With Chitin-Binding Protein-Mediated Lysine Decarboxylase Immobilization
por: Zhou, Ning, et al.
Publicado: (2020)

Thixotropic Supramolecular Gel Based on l-Lysine Derivatives
por: Suzuki, Masahiro, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_milhge7gsc6deb2g26apptfl2f