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Effects of Chronic Kidney Disease on Nanomechanics of the Endothelial Glycocalyx Are Mediated by the Mineralocorticoid Receptor

Endothelial mechanics control vascular reactivity and are regulated by the mineralocorticoid receptor (MR) and its downstream target, the epithelial Na(+) channel (ENaC). Endothelial dysfunction is a hallmark of chronic kidney disease (CKD), but its mechanisms are poorly understood. We hypothesized...

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Detalles Bibliográficos
Autores principales: Fels, Benedikt, Beyer, Arne, Cazaña-Pérez, Violeta, Giraldez, Teresa, Navarro-González, Juan F., de la Rosa, Diego Alvarez, Schaefer, Franz, Bayazit, Aysun K., Obrycki, Łukasz, Ranchin, Bruno, Holle, Johannes, Querfeld, Uwe, Kusche-Vihrog, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503126/
https://www.ncbi.nlm.nih.gov/pubmed/36142571
http://dx.doi.org/10.3390/ijms231810659