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Effects of Chronic Kidney Disease on Nanomechanics of the Endothelial Glycocalyx Are Mediated by the Mineralocorticoid Receptor
Endothelial mechanics control vascular reactivity and are regulated by the mineralocorticoid receptor (MR) and its downstream target, the epithelial Na(+) channel (ENaC). Endothelial dysfunction is a hallmark of chronic kidney disease (CKD), but its mechanisms are poorly understood. We hypothesized...
Autores principales: | Fels, Benedikt, Beyer, Arne, Cazaña-Pérez, Violeta, Giraldez, Teresa, Navarro-González, Juan F., de la Rosa, Diego Alvarez, Schaefer, Franz, Bayazit, Aysun K., Obrycki, Łukasz, Ranchin, Bruno, Holle, Johannes, Querfeld, Uwe, Kusche-Vihrog, Kristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503126/ https://www.ncbi.nlm.nih.gov/pubmed/36142571 http://dx.doi.org/10.3390/ijms231810659 |
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