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Nano-Based Co-Delivery System for Treatment of Rheumatoid Arthritis
A systemic autoimmune condition known as rheumatoid arthritis (RA) has a significant impact on patients’ quality of life. Given the complexity of RA’s biology, no single treatment can totally block the disease’s progression. The combined use of co-delivery regimens integrating various diverse mechan...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503141/ https://www.ncbi.nlm.nih.gov/pubmed/36144709 http://dx.doi.org/10.3390/molecules27185973 |
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author | Zhang, Shixin Zhang, Miaomiao Li, Xiangyu Li, Ge Yang, Bo Lu, Xinyue Gao, Yang Sun, Fengying |
author_facet | Zhang, Shixin Zhang, Miaomiao Li, Xiangyu Li, Ge Yang, Bo Lu, Xinyue Gao, Yang Sun, Fengying |
author_sort | Zhang, Shixin |
collection | PubMed |
description | A systemic autoimmune condition known as rheumatoid arthritis (RA) has a significant impact on patients’ quality of life. Given the complexity of RA’s biology, no single treatment can totally block the disease’s progression. The combined use of co-delivery regimens integrating various diverse mechanisms has been widely acknowledged as a way to make up for the drawbacks of single therapy. These days, co-delivery systems have been frequently utilized for co-treatment, getting over drug limitations, imaging of inflammatory areas, and inducing reactions. Various small molecules, nucleic acid drugs, and enzyme-like agents intended for co-delivery are frequently capable of producing the ability to require positive outcomes. In addition, the excellent response effect of phototherapeutic agents has led to their frequent use for delivery together with chemotherapeutics. In this review, we discuss different types of nano-based co-delivery systems and their advantages, limitations, and future directions. In addition, we review the prospects and predicted challenges for the combining of phototherapeutic agents with conventional drugs, hoping to provide some theoretical support for future in-depth studies of nano-based co-delivery systems and phototherapeutic agents. |
format | Online Article Text |
id | pubmed-9503141 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95031412022-09-24 Nano-Based Co-Delivery System for Treatment of Rheumatoid Arthritis Zhang, Shixin Zhang, Miaomiao Li, Xiangyu Li, Ge Yang, Bo Lu, Xinyue Gao, Yang Sun, Fengying Molecules Review A systemic autoimmune condition known as rheumatoid arthritis (RA) has a significant impact on patients’ quality of life. Given the complexity of RA’s biology, no single treatment can totally block the disease’s progression. The combined use of co-delivery regimens integrating various diverse mechanisms has been widely acknowledged as a way to make up for the drawbacks of single therapy. These days, co-delivery systems have been frequently utilized for co-treatment, getting over drug limitations, imaging of inflammatory areas, and inducing reactions. Various small molecules, nucleic acid drugs, and enzyme-like agents intended for co-delivery are frequently capable of producing the ability to require positive outcomes. In addition, the excellent response effect of phototherapeutic agents has led to their frequent use for delivery together with chemotherapeutics. In this review, we discuss different types of nano-based co-delivery systems and their advantages, limitations, and future directions. In addition, we review the prospects and predicted challenges for the combining of phototherapeutic agents with conventional drugs, hoping to provide some theoretical support for future in-depth studies of nano-based co-delivery systems and phototherapeutic agents. MDPI 2022-09-14 /pmc/articles/PMC9503141/ /pubmed/36144709 http://dx.doi.org/10.3390/molecules27185973 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Zhang, Shixin Zhang, Miaomiao Li, Xiangyu Li, Ge Yang, Bo Lu, Xinyue Gao, Yang Sun, Fengying Nano-Based Co-Delivery System for Treatment of Rheumatoid Arthritis |
title | Nano-Based Co-Delivery System for Treatment of Rheumatoid Arthritis |
title_full | Nano-Based Co-Delivery System for Treatment of Rheumatoid Arthritis |
title_fullStr | Nano-Based Co-Delivery System for Treatment of Rheumatoid Arthritis |
title_full_unstemmed | Nano-Based Co-Delivery System for Treatment of Rheumatoid Arthritis |
title_short | Nano-Based Co-Delivery System for Treatment of Rheumatoid Arthritis |
title_sort | nano-based co-delivery system for treatment of rheumatoid arthritis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503141/ https://www.ncbi.nlm.nih.gov/pubmed/36144709 http://dx.doi.org/10.3390/molecules27185973 |
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