Soluble CCR2 gene therapy controls joint inflammation, cartilage damage, and the progression of osteoarthritis by targeting MCP-1 in a monosodium iodoacetate (MIA)-induced OA rat model

BACKGROUND: Osteoarthritis (OA) is the most common type of degenerative arthritis and affects the entire joint, causing pain, joint inflammation, and cartilage damage. Various risk factors are implicated in causing OA, and in recent years, a lot of research and interest have been directed toward chr...

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Detalles Bibliográficos
Autores principales: Na, Hyun Sik, Lee, Seon-Yeong, Lee, Dong Hwan, Woo, Jin Seok, Choi, Si-Young, Cho, Keun-Hyung, Kim, Seon Ae, Go, Eun Jeong, Lee, A Ram, Choi, Jeong-Won, Kim, Seok Jung, Cho, Mi-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503236/
https://www.ncbi.nlm.nih.gov/pubmed/36138477
http://dx.doi.org/10.1186/s12967-022-03515-3

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