Correlation of plasma cell assessment by phenotypic methods and molecular profiles by NGS in patients with plasma cell dyscrasias

BACKGROUND: Next-generation sequencing (NGS) detects somatic mutations in a high proportion of plasma cell dyscrasias (PCD), but is currently not integrated into diagnostic routine. We correlated NGS data with degree of bone marrow (BM) involvement by cytomorphology (BMC), histopathology (BMH), and...

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Detalles Bibliográficos
Autores principales: Rebmann Chigrinova, Ekaterina, Porret, Naomi A., Andres, Martin, Wiedemann, Gertrud, Banz, Yara, Legros, Myriam, Pollak, Matthias, Oppliger Leibundgut, Elisabeth, Pabst, Thomas, Bacher, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503268/
https://www.ncbi.nlm.nih.gov/pubmed/36138464
http://dx.doi.org/10.1186/s12920-022-01346-1

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