Cargando…
Binding of Natural Inhibitors to Respiratory Complex I
NADH:ubiquinone oxidoreductase (respiratory complex I) is a redox-driven proton pump with a central role in mitochondrial oxidative phosphorylation. The ubiquinone reduction site of complex I is located in the matrix arm of this large protein complex and connected to the membrane via a tunnel. A var...
Autores principales: | Schiller, Jonathan, Zickermann, Volker |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503403/ https://www.ncbi.nlm.nih.gov/pubmed/36145309 http://dx.doi.org/10.3390/ph15091088 |
Ejemplares similares
-
Ubiquinone Binding and Reduction by Complex I—Open Questions and Mechanistic Implications
por: Galemou Yoga, Etienne, et al.
Publicado: (2021) -
Accessory Subunits of the Matrix Arm of Mitochondrial Complex I with a Focus on Subunit NDUFS4 and Its Role in Complex I Function and Assembly
por: Kahlhöfer, Flora, et al.
Publicado: (2021) -
Insights into complex I assembly: Function of NDUFAF1 and a link with cardiolipin remodeling
por: Schiller, Jonathan, et al.
Publicado: (2022) -
Cryo-EM structure of respiratory complex I at work
por: Parey, Kristian, et al.
Publicado: (2018) -
High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease
por: Parey, Kristian, et al.
Publicado: (2019)