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UV-Induced Somatic Mutations Driving Clonal Evolution in Healthy Skin, Nevus, and Cutaneous Melanoma

Introduction: Due to its aggressiveness, cutaneous melanoma (CM) is responsible for most skin cancer-related deaths worldwide. The origin of CM is closely linked to the appearance of UV-induced somatic mutations in melanocytes present in normal skin or in CM precursor lesions (nevi or dysplastic nev...

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Detalles Bibliográficos
Autores principales: Loras, Alba, Gil-Barrachina, Marta, Marqués-Torrejón, María Ángeles, Perez-Pastor, Gemma, Martinez-Cadenas, Conrado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503451/
https://www.ncbi.nlm.nih.gov/pubmed/36143375
http://dx.doi.org/10.3390/life12091339

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