Upregulated Apelin Signaling in Pancreatic Cancer Activates Oncogenic Signaling Pathways to Promote Tumor Development

Despite decades of effort in understanding pancreatic ductal adenocarcinoma (PDAC), there is still a lack of innovative targeted therapies for this devastating disease. Herein, we report the expression of apelin and its receptor, APJ, in human pancreatic adenocarcinoma and its protumoral function. A...

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Detalles Bibliográficos
Autores principales: Chaves-Almagro, Carline, Auriau, Johanna, Dortignac, Alizée, Clerc, Pascal, Lulka, Hubert, Deleruyelle, Simon, Projetti, Fabrice, Nakhlé, Jessica, Frances, Audrey, Berta, Judit, Gigoux, Véronique, Fourmy, Daniel, Dufresne, Marlène, Gomez-Brouchet, Anne, Guillermet-Guibert, Julie, Cordelier, Pierre, Knibiehler, Bernard, Jockers, Ralf, Valet, Philippe, Audigier, Yves, Masri, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503500/
https://www.ncbi.nlm.nih.gov/pubmed/36142542
http://dx.doi.org/10.3390/ijms231810600

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