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Non-Viral Delivery of CRISPR/Cas Cargo to the Retina Using Nanoparticles: Current Possibilities, Challenges, and Limitations
The discovery of the CRISPR/Cas system and its development into a powerful genome engineering tool have revolutionized the field of molecular biology and generated excitement for its potential to treat a wide range of human diseases. As a gene therapy target, the retina offers many advantages over o...
Autores principales: | Salman, Ahmed, Kantor, Ariel, McClements, Michelle E., Marfany, Gemma, Trigueros, Sonia, MacLaren, Robert E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503525/ https://www.ncbi.nlm.nih.gov/pubmed/36145593 http://dx.doi.org/10.3390/pharmaceutics14091842 |
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