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Peg-Grafted Liposomes for L-Asparaginase Encapsulation
L-asparaginase (ASNase) is an important biological drug used to treat Acute Lymphoblastic Leukemia (ALL). It catalyzes the hydrolysis of L-asparagine (Asn) in the bloodstream and, since ALL cells cannot synthesize Asn, protein synthesis is impaired leading to apoptosis. Despite its therapeutic impor...
Autores principales: | de Souza Guimarães, Marina, Cachumba, Jorge Javier Muso, Bueno, Cecilia Zorzi, Torres-Obreque, Karin Mariana, Lara, Grace Verónica Ruiz, Monteiro, Gisele, Barbosa, Leandro Ramos Souza, Pessoa, Adalberto, Rangel-Yagui, Carlota de Oliveira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503594/ https://www.ncbi.nlm.nih.gov/pubmed/36145567 http://dx.doi.org/10.3390/pharmaceutics14091819 |
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