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The First Two Cases of Monkeypox Infection in MSM in Bahia, Brazil, and Viral Sequencing

Monkeypox infection is rapidly spreading across the world. Despite the increasing number of cases, only a few reports have been published, and most are on people living without HIV. We report here the first two cases of monkeypox infection in Bahia, Brazil, one of them in a person living with HIV, o...

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Autores principales: Brites, Carlos, Deminco, Felice, Sá, Marcia Sampaio, Brito, Jean Tadeu, Luz, Estela, Stocker, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503704/
https://www.ncbi.nlm.nih.gov/pubmed/36146654
http://dx.doi.org/10.3390/v14091841
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author Brites, Carlos
Deminco, Felice
Sá, Marcia Sampaio
Brito, Jean Tadeu
Luz, Estela
Stocker, Andreas
author_facet Brites, Carlos
Deminco, Felice
Sá, Marcia Sampaio
Brito, Jean Tadeu
Luz, Estela
Stocker, Andreas
author_sort Brites, Carlos
collection PubMed
description Monkeypox infection is rapidly spreading across the world. Despite the increasing number of cases, only a few reports have been published, and most are on people living without HIV. We report here the first two cases of monkeypox infection in Bahia, Brazil, one of them in a person living with HIV, on stable treatment. Both cases had a similar evolution, with a limited number of lesions and mild symptoms, with a complete recovery after 7–10 days. The potential route of transmission was via oral sex for the first case and was undefined for the second one. Both cases were confirmed through detection of the viral genome by PCR, and the partial sequence of the first case indicates the infection was caused by the West African clade. These cases confirm that monkeypox infection is currently being transmitted in Brazil and that people living with HIV on stable treatment are not likely to present a more severe form of monkeypox.
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spelling pubmed-95037042022-09-24 The First Two Cases of Monkeypox Infection in MSM in Bahia, Brazil, and Viral Sequencing Brites, Carlos Deminco, Felice Sá, Marcia Sampaio Brito, Jean Tadeu Luz, Estela Stocker, Andreas Viruses Case Report Monkeypox infection is rapidly spreading across the world. Despite the increasing number of cases, only a few reports have been published, and most are on people living without HIV. We report here the first two cases of monkeypox infection in Bahia, Brazil, one of them in a person living with HIV, on stable treatment. Both cases had a similar evolution, with a limited number of lesions and mild symptoms, with a complete recovery after 7–10 days. The potential route of transmission was via oral sex for the first case and was undefined for the second one. Both cases were confirmed through detection of the viral genome by PCR, and the partial sequence of the first case indicates the infection was caused by the West African clade. These cases confirm that monkeypox infection is currently being transmitted in Brazil and that people living with HIV on stable treatment are not likely to present a more severe form of monkeypox. MDPI 2022-08-23 /pmc/articles/PMC9503704/ /pubmed/36146654 http://dx.doi.org/10.3390/v14091841 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Brites, Carlos
Deminco, Felice
Sá, Marcia Sampaio
Brito, Jean Tadeu
Luz, Estela
Stocker, Andreas
The First Two Cases of Monkeypox Infection in MSM in Bahia, Brazil, and Viral Sequencing
title The First Two Cases of Monkeypox Infection in MSM in Bahia, Brazil, and Viral Sequencing
title_full The First Two Cases of Monkeypox Infection in MSM in Bahia, Brazil, and Viral Sequencing
title_fullStr The First Two Cases of Monkeypox Infection in MSM in Bahia, Brazil, and Viral Sequencing
title_full_unstemmed The First Two Cases of Monkeypox Infection in MSM in Bahia, Brazil, and Viral Sequencing
title_short The First Two Cases of Monkeypox Infection in MSM in Bahia, Brazil, and Viral Sequencing
title_sort first two cases of monkeypox infection in msm in bahia, brazil, and viral sequencing
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503704/
https://www.ncbi.nlm.nih.gov/pubmed/36146654
http://dx.doi.org/10.3390/v14091841
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